Senior Cryo-EM Structural Biologist (Remote)

Placements24; Mbombela (Nelspruit); Hybrid; ZAR 3,005,000 - 4,341,000; Full time

Benefits offered by this job

Health insurance

Retirement contributions

Paid time off

Remote work flexibility

Job summary

Placements24 is seeking a Lead Structural Biologist with deep Cryo-EM expertise to drive high-resolution drug discovery projects remotely. You will guide experimental design, data analysis, and cross-functional collaboration across international sites.

The role emphasizes leadership, mentorship of junior scientists, and staying at the forefront of Cryo-EM techniques, while enjoying a remote-first work environment and flexible scheduling.

Qualifications

• PhD with strong Cryo-EM focus.
• 8+ years of hands-on experience in structural biology and Cryo-EM.
• Proven ability to solve high-resolution structures of challenging protein complexes.
• Extensive experience with RELION, cisTEM, CryoSPARC for data processing.
• Experience in protein expression and purification methods.
• Strong leadership, communication, and remote collaboration skills.

Responsibilities

• Lead Cryo-EM projects for high-resolution structure determination.
• Develop and optimize sample prep for challenging biomolecules.
• Oversee data collection on Cryo-EM instruments; coordinate via remote/partner labs.
• Process and interpret Cryo-EM data to inform drug design.
• Mentor junior scientists and contribute to strategy.
• Collaborate with cross-functional teams in a remote setting.
• Stay updated on Cryo-EM advancements.
• Manage multiple projects and prioritize tasks.

Skills

Cryo-EM proficiency

Relion/CryoSPARC workflows

Protein expression & purification

Data analysis & interpretation

Remote leadership

Scientific communication

Education

PhD in Structural Biology / Biochemistry / Biophysics

Tools

RELION

cisTEM

CryoSPARC

Job description

Placements24 is seeking a Lead Structural Biologist with deep Cryo-EM expertise to drive high-resolution drug discovery projects remotely. You will guide experimental design, data analysis, and cross-functional collaboration across international sites.

The role emphasizes leadership, mentorship of junior scientists, and staying at the forefront of Cryo-EM techniques, while enjoying a remote-first work environment and flexible scheduling.