Remote Lead Structural Biologist: Drug Discovery Leader

Placements24; Sandton; Hybrid; ZAR 1,200,000 - 1,800,000; Full time

Benefits offered by this job

Health insurance

Dental insurance

Vision insurance

Remote work flexibility

Job summary

Placements24 is recruiting a Lead Structural Biologist to drive insights into molecular mechanisms from a fully remote location. You will direct projects using X-ray crystallography, cryo-EM, and NMR, and collaborate with discovery teams worldwide to guide lead optimization.

The role demands 8+ years post-PhD experience, strong leadership, and the ability to communicate complex data clearly in a remote, global setup. A competitive package and growth opportunities are offered.

Qualifications

• PhD in Structural Biology or related field.
• Post-PhD experience of 8+ years in structural biology, with leadership experience.
• Hands-on experience with X-ray crystallography and/or cryo-EM.
• Strong data analysis and structure determination skills.
• Excellent communication and collaboration in global teams.

Responsibilities

• Lead structural biology projects to determine high-resolution structures of targets and complexes.
• Develop and optimize protein expression, purification, and crystallization/sample prep protocols for cryo-EM.
• Interpret structural data to aid structure-based drug design.
• Collaborate with computational chemists, medicinal chemists, and biologists.
• Manage remote team timelines, resources, and deliverables.
• Mentor junior scientists and researchers.
• Stay current with advances in structural biology techniques and instrumentation.
• Present findings to internal teams and external audiences.
• Contribute to strategic direction of structural biology initiatives.

Skills

Leadership

Remote collaboration

Scientific communication

Mentoring

Project management

Education

PhD in Structural Biology

Biophysics/Biochemistry background

Tools

X-ray crystallography

Cryo-EM

NMR spectroscopy

Structure determination software

Job description

Placements24 is recruiting a Lead Structural Biologist to drive insights into molecular mechanisms from a fully remote location. You will direct projects using X-ray crystallography, cryo-EM, and NMR, and collaborate with discovery teams worldwide to guide lead optimization.

The role demands 8+ years post-PhD experience, strong leadership, and the ability to communicate complex data clearly in a remote, global setup. A competitive package and growth opportunities are offered.