Clinical Trials Manager — Remote, Phase I–IV

Placements24; Kempton Park; Hybrid; ZAR 900,000 - 1,300,000; Full time

Benefits offered by this job

Health insurance

Retirement savings plan

Performance-based bonus

Professional development opportunities

Job summary

Placements24 is seeking a Clinical Trials Manager in Gauteng to oversee planning, execution, and completion of Phase I–IV trials. The role requires strong project leadership and a deep understanding of regulatory requirements to drive compliant, efficient research programs.

The successful candidate will manage sites, vendors, data, and multidisciplinary teams across locations, ensuring timelines, budgets, and quality meet corporate standards and patient safety remains paramount.

Qualifications

• Bachelor's degree in Life Sciences, Nursing, Pharmacy, or related; Master's preferred.
• Minimum 5 years' experience in clinical trial management in pharma/biotech.
• Experience in all phases of clinical trials (Phase I–IV).
• Knowledge of GCP, ICH guidelines, and regulatory submission processes.
• Strong project management and ability to manage multiple complex projects.
• Excellent leadership, communication, and interpersonal skills.
• Experience in data management and statistical analysis interpretation.
• Willingness to travel to investigative sites and meetings.
• Ability to work effectively in a remote setting, managing teams across locations.
• Familiarity with regulatory environment in Tembisa, Gauteng is a plus.

Responsibilities

• Develop and manage clinical trial protocols, budgets, and timelines.
• Oversee selection, training, and management of clinical investigative sites and site staff.
• Ensure adherence to Good Clinical Practice (GCP) guidelines, FDA regulations, and other applicable local and international regulatory requirements.
• Monitor clinical trial progress, identify potential risks, and implement mitigation strategies.
• Manage data collection, review, and database lock processes.
• Coordinate with internal departments, including regulatory affairs, medical affairs, and pharmacovigilance.
• Prepare and present trial status reports to senior management and key stakeholders.
• Manage vendor relationships and ensure successful execution of outsourced activities.
• Facilitate site audits and regulatory inspections.
• Contribute to the development and improvement of clinical trial operational procedures.

Skills

Clinical trial management

Leadership

Communication

Interpersonal skills

Project management

Remote team management

Regulatory knowledge

Education

Bachelor's degree in Life Sciences/Nursing/Pharmacy

Master's degree or higher (preferred)

Job description

Placements24 is seeking a Clinical Trials Manager in Gauteng to oversee planning, execution, and completion of Phase I–IV trials. The role requires strong project leadership and a deep understanding of regulatory requirements to drive compliant, efficient research programs.

The successful candidate will manage sites, vendors, data, and multidisciplinary teams across locations, ensuring timelines, budgets, and quality meet corporate standards and patient safety remains paramount.