Analytical Development Chemist

Placements24; Mbombela (Nelspruit); Hybrid; ZAR 420,000 - 540,000; Full time

Benefits offered by this job

Hybrid work model

Health and retirement benefits

Education and development

Job summary

Placements24 is seeking an Analytical Development Chemist for our client in Nelspruit to develop, validate and transfer analytical methods for drug substances and products, supporting development and commercialization while ensuring quality and compliance.

The role requires 3+ years in pharmaceutical analytical method development, expertise in HPLC/GC and spectroscopy, and an ICH-driven approach to testing with a hybrid work arrangement in Nelspruit.

Qualifications

• Bachelor's or Master's degree in Chemistry, Analytical Chemistry, or a related field.
• Minimum of 3 years of experience in analytical method development and validation in the pharmaceutical industry.
• Proficiency with chromatographic techniques (HPLC, GC) and associated detectors.
• Experience with spectroscopy (UV-Vis, IR, Mass Spectrometry) is highly desirable.
• Solid understanding of ICH guidelines and regulatory requirements for analytical testing.
• Strong analytical thinking, problem-solving skills, and attention to detail.

Responsibilities

• Develop and validate analytical methods for drug substances and products using techniques such as HPLC, GC, UV-Vis, and dissolution testing.
• Transfer validated methods to Quality Control laboratories for routine testing.
• Perform method troubleshooting and optimization to improve robustness and efficiency.
• Characterize impurities and degradation products using advanced analytical instrumentation.
• Author method validation reports, analytical procedures, and specifications.
• Stay updated on regulatory guidelines (e.g., ICH) and analytical technologies.

Skills

Analytical method development

Validation

HPLC

GC

UV-Vis

IR

Mass spec

ICH guidelines

Analytical thinking

Problem solving

Attention to detail

Education

BSc Chemistry

MSc Chemistry

Job description

Our client is seeking a skilled Analytical Development Chemist to join their expanding laboratory services in Nelspruit . This role focuses on developing, validating, and transferring analytical methods for raw materials, intermediates, and finished pharmaceutical products. You will utilize your expertise in various analytical techniques to ensure the quality, purity, and potency of drug substances and products, supporting both development and commercialization efforts. This is a fantastic opportunity to contribute to critical quality control processes within a leading pharmaceutical organization.

Key Responsibilities

• Develop and validate analytical methods for drug substances and products using techniques such as HPLC, GC, UV-Vis, and dissolution testing.
• Transfer validated methods to Quality Control laboratories for routine testing.
• Perform method troubleshooting and optimization to improve robustness and efficiency.
• Characterize impurities and degradation products using advanced analytical instrumentation.
• Author method validation reports, analytical procedures, and specifications.
• Stay updated on regulatory guidelines (e.g., ICH) and analytical technologies.

Requirements

• Bachelor's or Master's degree in Chemistry, Analytical Chemistry, or a related field.
• Minimum of 3 years of experience in analytical method development and validation in the pharmaceutical industry.
• Proficiency with chromatographic techniques (HPLC, GC) and associated detectors.
• Experience with spectroscopy (UV-Vis, IR, Mass Spectrometry) is highly desirable.
• Solid understanding of ICH guidelines and regulatory requirements for analytical testing.
• Strong analytical thinking, problem-solving skills, and attention to detail.

Benefits

• Competitive salary and annual performance bonus.
• Comprehensive health and retirement benefits package.
• Support for continuing education and professional development opportunities.
• Hybrid work model providing work-life balance in Nelspruit .
• Access to modern analytical instrumentation and laboratory resources.
• Collaborative and growth-oriented work environment.