Staff Bioinformatics Scientist MRD Oncology Algorithms

Oncology Voice Network LLC; United States; Hybrid; USD 156,000 - 233,000; Full time

Benefits offered by this job

Health/dental/vision

Retirement benefits

Paid time off

Genomics sequencing access

Job summary

Illumina in the United States is seeking a Staff Bioinformatics Scientist focused on oncology MRD algorithm development. You will prototype NGS-based methods to detect minimal residual disease in ctDNA, leveraging signals from variant calling, copy number, fragmentomics, and methylation.

The role includes collaborating with internal and external teams, guiding experiments, and enhancing therapy-selection algorithms across variant types, with flexible remote options within the US and a strong

Qualifications

• PhD in bioinformatics, computation biology, statistics, math or related field with 3+ years industry experience.
• Fluency in at least two of statistics, common bioinformatics methods NGS analysis, and oncology.
• Proven track-record with developing bioinformatics NGS algorithms beyond leveraging already existing tools.
• Fluency in programming languages such as Python. Experience with C++ is desired.
• Good communication skills to contribute to cross functional project teams and work with stakeholders.

Responsibilities

• Prototype novel NGS algorithms for clinical oncology use cases such as MRD.
• Assess and improve existing secondary analysis algorithms for variant and biomarker detection.
• In collaboration with external and internal experimental teams, design and analyze experiments to support existing or new Illumina oncology assays.
• Provide technical guidance to internal and external collaborators.
• Participate in cross functional assay and algorithm R&D teams with minimal oversight.
• Effectively communicate plans and results across functions.

Skills

Python programming

Statistics

Bioinformatics methods

Oncology knowledge

NGS data analysis

Communication

Education

PhD in bioinformatics or related field

Tools

C++

Job description

Illumina in the United States is seeking a Staff Bioinformatics Scientist focused on oncology MRD algorithm development. You will prototype NGS-based methods to detect minimal residual disease in ctDNA, leveraging signals from variant calling, copy number, fragmentomics, and methylation.

The role includes collaborating with internal and external teams, guiding experiments, and enhancing therapy-selection algorithms across variant types, with flexible remote options within the US and a strong