Remote Staff Bioinformatics Scientist – MRD Oncology

Illumina; San Diego, Northern (CA, KY); Hybrid; USD 156,000 - 233,000; Full time

Benefits offered by this job

Health/dental/vision

Retirement benefits

Paid time off

Family planning

Job summary

Illumina in the United States is seeking a Staff Bioinformatics Scientist focused on oncology and minimal residual disease (MRD) algorithm development. This role involves building and refining algorithms that detect MRD in ctDNA, integrating signals from variant calling, copy number analysis, fragmentomics, and methylation, and collaborating with clinical and research teams.

The position may be performed remotely within the US, with expectations to align with Pacific Time for meetings.

Qualifications

• PhD in bioinformatics, computation biology, statistics, math or related field with 3+ years industry experience.
• Fluency in at least two of: statistics, common bioinformatics methods, NGS analysis, and oncology.
• Proven track-record of developing bioinformatics NGS algorithms beyond leveraging already existing tools.
• Fluency in programming languages such as Python; C++ is a plus.
• Good communication skills to contribute to cross functional project teams.

Responsibilities

• Prototype novel NGS algorithms for clinical oncology use cases such as MRD.
• Assess and improve existing secondary analysis algorithms for variant and biomarker detection.
• In collaboration with external and internal experimental teams, design and analyze experiments to support existing or new Illumina oncology assays.
• Provide technical guidance to internal and external collaborators.
• Participate in cross functional assay and algorithm R&D teams with minimal oversight.
• Effectively communicate plans and results across functions.

Skills

Statistics

Bioinformatics methods

NGS analysis

Oncology

Python

Education

PhD in bioinformatics / computational biology / statistics / math or related field

Tools

C++

Job description

Illumina in the United States is seeking a Staff Bioinformatics Scientist focused on oncology and minimal residual disease (MRD) algorithm development. This role involves building and refining algorithms that detect MRD in ctDNA, integrating signals from variant calling, copy number analysis, fragmentomics, and methylation, and collaborating with clinical and research teams.

The position may be performed remotely within the US, with expectations to align with Pacific Time for meetings.