Bioinformatics Scientist, NGS & MRD in Oncology

Quest Diagnostics; Baltimore (MD); Hybrid; USD 80,000 - 100,000; Full time

Benefits offered by this job

Health insurance

Vacation and health/flex time

401(k) with company match

Education assistance through Quest for

Job summary

Quest Diagnostics seeks a bioinformatics scientist to design and implement pipelines for MRD testing and clinical NGS assays. You will collaborate with wet lab, R&D, and software teams to ensure scalable, compliant workflows for patient testing and reporting.

The role requires 5+ years in NGS data analysis, PhD or MS with relevant industry experience, and strong Python/R skills. Hybrid work is offered from Baltimore, MD or other listed offices.

Qualifications

• Proficiency in bioinformatics pipeline workflow management, particularly Nextflow (preferred), Cromwell, or CWL.
• Expertise developing pipelines for cloud-based computational environments (AWS, or similar).
• Demonstrated ability to work with regulated clinical or diagnostic environments (e.g., CLIA, CAP, or FDA submissions)

Responsibilities

• Design, develop, and optimize bioinformatics pipelines for MRD test development and clinical deployment.
• Analyze high throughput NGS data and drive performance and scientific insights to support research and development of on-market and upcoming products.
• Collaborate with laboratory scientists, clinicians, and software engineers to validate and integrate bioinformatics solutions into clinical workflows.
• Apply software engineering best practices, contributing to the scalability, robustness, and maintainability of bioinformatics pipelines.
• Document and validate bioinformatics systems in compliance with regulatory and quality standards for clinical diagnostics.
• Stay current with advancements in oncology genomics, liquid biopsy, and computational biology methods to inform innovation and future product enhancement.
• Identify problems, investigate alternatives and recommend possible courses of action, contribute to technical decisions.
• Prepare and present information at project meetings, scientific & technical meetings/conferences, and to customers.

Skills

Python

R

Analytical thinking

Problem solving

Collaboration

Education

Ph.D. in Bioinformatics, computational biology, genomics, or related fields

MS with extensive industry experience

Tools

Nextflow

Cromwell

CW L

AWS

Job description

Quest Diagnostics seeks a bioinformatics scientist to design and implement pipelines for MRD testing and clinical NGS assays. You will collaborate with wet lab, R&D, and software teams to ensure scalable, compliant workflows for patient testing and reporting.

The role requires 5+ years in NGS data analysis, PhD or MS with relevant industry experience, and strong Python/R skills. Hybrid work is offered from Baltimore, MD or other listed offices.