Spatial Protein Assay Scientist for Tissue Imaging

10x Genomics, Inc.; Pleasanton (CA); Hybrid; USD 123,000 - 167,000; Full time

Benefits offered by this job

Equity grants

Health and retirement benefits

Annual bonus program

Job summary

10x Genomics, Inc. in Pleasanton, CA seeks a multidisciplinary scientist for Spatial Biology to map proteins and other biomolecules directly within intact tissue.

You will design, run, and troubleshoot experiments to develop spatial multiomics assays, collaborating with chemistry, computational biology, software and engineering teams. Ideal candidates will have a PhD in cell biology or related field and 2+ years in proteomics or in situ spatial techniques, with strong data analysis and

Qualifications

• PhD required in Cell Biology, Immunology, Biochemistry or related field.
• 2+ years hands-on experience in proteomics, in situ hybridization or other imaging based spatial techniques.
• Experience with tissue processing, histology, immunohistochemistry, cryosectioning, immunofluorescence including characterization by surface markers or gene expression.
• Experience working with antibodies, including mAb QC, conjugation and/or functional testing.
• Strong analytical background; excellent organizational, written and oral communication skills.
• Ability to thrive in a fast-paced, changing environment; strong troubleshooting skills.
• Desire to build game-changing technologies in life sciences.

Responsibilities

• Contribute to optimization of tissue handling and processing protocols for protein staining, including FFPE samples.
• Design and execute experiments using imaging and biochemistry platforms for spatial technology platforms.
• Analyze and report data via documentation and internal presentations.
• Collaborate with computational biologists and software engineers to interpret assay data.

Skills

Proteomics

In situ

IHC

Cryosectioning

Immunofluorescence

Antibody conjugation

Data analysis

Troubleshooting

Communication

Multiplex assays

R/Python

Education

PhD in Cell Biology or related field

Job description

10x Genomics, Inc. in Pleasanton, CA seeks a multidisciplinary scientist for Spatial Biology to map proteins and other biomolecules directly within intact tissue.

You will design, run, and troubleshoot experiments to develop spatial multiomics assays, collaborating with chemistry, computational biology, software and engineering teams. Ideal candidates will have a PhD in cell biology or related field and 2+ years in proteomics or in situ spatial techniques, with strong data analysis and