Lead Scientist Spatial Proteomics & Tissue Imaging

10x Genomics, Inc.

Pleasanton (CA)

Hybrid

USD 150,000 - 210,000

Full time

14 days+

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Job summary

10x Genomics, Inc. is seeking a multidisciplinary scientist to drive spatial biology R&D and product development.

You will leverage cell biology, proteomics, and immunology expertise to optimize tissue-based assays and contribute to cross-disciplinary teams across chemistry, computational biology, software, and microfluidics. The ideal candidate has a PhD with 5+ years in proteomics/imaging and hands-on experience with high-plex multiplexing and tissue-based techniques, in a fast-paced

Qualifications

  • PhD in Molecular/Cell Biology, Immunology, Biochemistry or related field.
  • 5+ years of proteomics, imaging and spatial techniques experience, in situ hybridization preferred.
  • Hands-on with high-plex protein multiplexing technology.
  • Tissue processing, histology, immunohistochemistry, cryosectioning, immunofluorescence.
  • Experience with antibodies and QC/conjugation testing.
  • Strong analytical and communication skills; able to work in cross-functional teams.

Responsibilities

  • Design and optimize tissue handling protocols for protein staining in FFPE samples.
  • Contribute to development and evaluation of spatial multiomics assays in tissues.
  • Perform experiments using imaging and biochemistry platforms; report results clearly.
  • Collaborate with computational biology and software engineers to interpret data.
  • Develop robust protocols for internal use across product development teams.

Skills

Analytical background
Written and verbal communication
Troubleshooting and problem solving
Fast-paced environment adaptability
High-plex protein multiplexing
Cross‑department collaboration
Tissue imaging data interpretation

Education

PhD in Molecular/Cell Biology or Immunology or Biochemistry

Tools

R
Python
Omics data analysis software

Job description

10x Genomics, Inc. is seeking a multidisciplinary scientist to drive spatial biology R&D and product development.

You will leverage cell biology, proteomics, and immunology expertise to optimize tissue-based assays and contribute to cross-disciplinary teams across chemistry, computational biology, software, and microfluidics. The ideal candidate has a PhD with 5+ years in proteomics/imaging and hands-on experience with high-plex multiplexing and tissue-based techniques, in a fast-paced

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