Spatial Biology Histotechnologist: High-Plex Imaging

Boehringer Ingelheim

Ridgefield (CT)

In loco

USD 85.000 - 120.000

Tempo pieno

4 giorni fa
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Descrizione del lavoro

Boehringer Ingelheim in Ridgefield, CT, seeks a Histotechnologist / Spatial Biology Specialist to build and expand spatial biology capabilities for preclinical biomarker discovery. The role blends histology, imaging, and data analysis to create high-quality spatial datasets.

The candidate will develop high-plex tissue assays, optimize antibody panels, and implement spatial profiling workflows across human and mouse tissues, collaborating with cross-functional teams to advance tumor

Competenze

  • Experience with high-plex tissue-based assays and antibody panel development.
  • Experience with spatial transcriptomics or related spatial gene-expression technologies.
  • Experience with quantitative microscopy or high-content tissue imaging.
  • Experience with image analysis, including tissue annotation, cell segmentation, phenotyping, and spatial measurements.
  • Proficiency in R, Python, or other data-analysis environments.

Mansioni

  • Develop, optimize, and execute high-plex tissue-based assays (e.g., multiplex immunofluorescence) in human and mouse tissues.
  • Design and optimize multiplex antibody panels, including controls, tissue-specific optimization, and assay performance.
  • Support spatial transcriptomics and emerging spatial profiling technologies with QC of assays and data.
  • Develop integrated workflows spanning tissue prep, staining, imaging, spatial profiling, and quantitative analysis.
  • Collaborate with computational teams to integrate spatial protein, RNA, imaging, and histopathology data.

Conoscenze

High-plex spatial technologies
Quantitative image analysis
Multiplex immunofluorescence
Tissue-based assay development

Formazione

Bachelor's or Master's degree in Biology/Histotechnology/Biomedical Sciences

Descrizione del lavoro

Boehringer Ingelheim in Ridgefield, CT, seeks a Histotechnologist / Spatial Biology Specialist to build and expand spatial biology capabilities for preclinical biomarker discovery. The role blends histology, imaging, and data analysis to create high-quality spatial datasets.

The candidate will develop high-plex tissue assays, optimize antibody panels, and implement spatial profiling workflows across human and mouse tissues, collaborating with cross-functional teams to advance tumor

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