Senior Staff Engineer, Downstream Bioprocess Innovation

USA - 3316 Takeda Development Center Americas, Inc.; Lexington (MA); On-site; USD 137,000 - 215,000; Full time

Job summary

Takeda in Lexington, MA is seeking a Senior Staff Engineer, Process Development to lead downstream bioprocess development, scale-up, and technology advancement for robust biotherapeutic manufacturing.

You will shape platform strategies, promote automation, PAT, and digital solutions, collaborate across R&D, manufacturing, quality, regulatory, and external partners, and mentor scientists and engineers in a development-focused environment.

Qualifications

• Pharmaceutical development experience in cGMP environments.
• Proven ability to lead cross-functional teams.
• Strong communication and problem-solving skills.

Responsibilities

• Lead downstream bioprocess development, optimization, scale-up, and tech development.
• Define strategies for design, intensification, automation, PAT, and new tech.
• Develop and characterize robust purification, filtration, chromatography, viral clearance, formulation.
• Solve complex challenges with data-driven approaches.
• Serve as subject-matter expert across downstream processing technologies.
• Advance digital data analysis and process modeling capabilities.
• Manage external partnerships and vendors to meet project goals.
• Mentor colleagues and strengthen team capabilities.
• Ensure alignment with business, manufacturing, quality, regulatory, and product goals.

Skills

Technical leadership

Communication

Problem solving

Collaboration

Data analysis

Process modeling

Automation

PAT

Digital infrastructure

Education

Bachelor's degree in relevant field

Master's degree in relevant field

Ph.D. in a related field

Job description

Takeda in Lexington, MA is seeking a Senior Staff Engineer, Process Development to lead downstream bioprocess development, scale-up, and technology advancement for robust biotherapeutic manufacturing.

You will shape platform strategies, promote automation, PAT, and digital solutions, collaborate across R&D, manufacturing, quality, regulatory, and external partners, and mentor scientists and engineers in a development-focused environment.