Downstream Bioprocess Engineer II (Purification)

Takeda Pharmaceutical Co.; Lexington (MA); On-site; USD 72,000 - 113,000; Full time

Job summary

Takeda Pharmaceutical Co. in Lexington, MA is seeking a Downstream Process Development Engineer II. This early-career role supports downstream biotherapeutics process development from micro to pilot scales, collaborating with senior engineers to execute studies and generate data.

You will document experiments, perform basic data analysis, and contribute to continuous improvement while adhering to quality and safety requirements. This position offers growth in a regulated manufacturing setting.

Qualifications

• Associate degree with 2+ years relevant experience or bachelor’s degree with relevant experience.
• Experience with chromatography, harvest, UF/DF, and viral clearance steps.
• Comfort with digital tools and AI-enabled processes for data analysis and documentation.
• Ability to follow detailed procedures and maintain accurate records.

Responsibilities

• Execute chromatography, harvest operations, UF/DF, and viral clearance experiments.
• Support downstream process development across micro to pilot scale.
• Maintain laboratory equipment and readiness of instruments.
• Collaborate with senior engineers to plan and execute larger experiments.
• Document work in electronic lab notebooks with clear records.
• Perform basic data analysis and present results in written form.

Skills

Chromatography

Harvest operations

UF/DF

Viral clearance

Data analysis

Technical writing

Documentation in ELN

Process development

Team collaboration

Education

Associate degree in chemical engineering or related

Bachelor’s degree in chemical engineering, chemistry, biochemistry, biotechnology or related

Tools

Electronic Laboratory Notebooks

Job description

Takeda Pharmaceutical Co. in Lexington, MA is seeking a Downstream Process Development Engineer II. This early-career role supports downstream biotherapeutics process development from micro to pilot scales, collaborating with senior engineers to execute studies and generate data.

You will document experiments, perform basic data analysis, and contribute to continuous improvement while adhering to quality and safety requirements. This position offers growth in a regulated manufacturing setting.