Senior Scientist, Quantitative Pharmacology

Genmab A/S; Princeton (NJ); Hybrid; USD 120,000 - 208,000; Full time

Benefits offered by this job

401(k) plan

Health benefits

Voluntary plans: critical illness, etc

Paid time off

Backup care resources

Tuition reimbursement

Lifestyle Spending Account

Job summary

Genmab is seeking a Scientist/Senior Scientist in Quantitative Pharmacology and Pharmacometrics to contribute pharmacometrics expertise across development programs. You will support population PK, exposure–response, PK-PD, PBPK, and survival modeling to inform dose selection and trial design, under guidance from senior colleagues.

This role offers hybrid work with 20%–40% remote work and opportunities for professional growth within a high-impact Clinical Pharmacology & Quantitative Science team.

Qualifications

• PhD in Clinical Pharmacology, Pharmacokinetics, Pharmaceutical Science or related discipline.
• For Scientist level, 0-2 years of relevant experience; For Senior Scientist level, 2+ years of relevant experience applying quantitative methods to drug development questions.
• Hands‑on experience with pharmacometrics and data analysis tools such as NONMEM, Monolix, R, or similar software.
• Ability to work with clinical and nonclinical data, perform model diagnostics, and generate clear, reproducible analyses.
• Understanding of antibody therapeutics development, oncology, or immunology is beneficial.
• Excellent written, verbal, and interpersonal communication skills, with the ability to explain quantitative concepts to multidisciplinary audiences.
• Strong problem‑solving skills, scientific curiosity, attention to detail, and the ability to thrive in a collaborative, fast‑paced biotechnology environment.

Responsibilities

• Plan, conduct, document, and quality-check routine pharmacometrics analyses under guidance from senior team members.
• Contribute to the development, validation, execution, and interpretation of population PK, exposure–response, PK-PD, PBPK, time-to-event, survival, disease progression models to support dose selection, regimen optimization, and trial design.
• Prepare model code, diagnostics, tables, figures, reports, and presentations in a reproducible and well-documented manner.
• Communicate the pharmacometrics analysis results to program teams to support data-driven decision-making process.
• Contribute quantitative clinical pharmacology and pharmacometrics content for regulatory submissions, including INDs, CTAs, and BLAs, and support responses to agency questions on modeling and simulation deliverables.
• Support the advancement of quantitative clinical pharmacology and pharmacometrics capabilities, including model-informed drug development approaches, tools, workflows, and best practices.

Skills

Communication

Team collaboration

Problem solving

Education

PhD in Clinical Pharmacology

Tools

NONMEM

Monolix

R

Job description

Genmab is seeking a Scientist/Senior Scientist in Quantitative Pharmacology and Pharmacometrics to contribute pharmacometrics expertise across development programs. You will support population PK, exposure–response, PK-PD, PBPK, and survival modeling to inform dose selection and trial design, under guidance from senior colleagues.

This role offers hybrid work with 20%–40% remote work and opportunities for professional growth within a high-impact Clinical Pharmacology & Quantitative Science team.