Senior Quantitative Pharmacology & Pharmacometrics Lead

Scorpion Therapeutics; Pennsylvania; On-site; USD 140,000 - 190,000; Full time

Job summary

Scorpion Therapeutics is seeking a quantitative pharmacology scientist to lead model-based translational efforts in cardiometabolic and related programs. You will design population PK/PD analyses, build mechanistic models, and guide dose selection and trial design in collaboration with multidisciplinary teams.

The role emphasizes cross-functional communication, expertise in pharmacometrics software, and ability to interpret complex data for decision-making across development stages.

Qualifications

• PhD/PharmD with 2+ years or MS with 4+ years in pharma, regulatory, or academia.
• Background in biopharmaceutics, pharmaceutical sciences, pharmacometrics or related fields.
• Experience with population PK and PK/PD analyses using pharmacometrics software.

Responsibilities

• Develop model-based strategies across programs to optimize dose, trial design, and go/no-go decisions.
• Represent QP2 across discovery and clinical development teams using quantitative approaches.
• Collaborate with internal teams and external vendors on study design, execution, and reporting.

Skills

Clinical study design

Pharmacokinetics

Pharmacodynamics

Data modeling

Visualization

Interdisciplinary collaboration

Machine learning

Pharmacotherapeutics

Education

Ph.D. or PharmD with 2+ years

MS with 4+ years

Tools

NONMEM

Monolix

Phoenix

Job description

Scorpion Therapeutics is seeking a quantitative pharmacology scientist to lead model-based translational efforts in cardiometabolic and related programs. You will design population PK/PD analyses, build mechanistic models, and guide dose selection and trial design in collaboration with multidisciplinary teams.

The role emphasizes cross-functional communication, expertise in pharmacometrics software, and ability to interpret complex data for decision-making across development stages.