Senior Scientist, Protein Assay Development – Spatial Biology

Scorpion Therapeutics; Pleasanton (CA); On-site; USD 150,000 - 230,000; Full time

Job summary

Scorpion Therapeutics is seeking a multidisciplinary scientist to advance spatial biology research and product development focused on high‑plex tissue proteomics and biomolecule mapping within intact tissues.

You will collaborate with chemistry, computational biology, software, engineering, and microfluidics teams, reporting to R&D leadership, to push the boundaries of tissue-based biomolecule mapping in a fast-paced environment.

Qualifications

• PhD in molecular/cell biology or related field.
• 5+ years in proteomics and tissue imaging with high‑plex multiplexing technologies.
• Hands-on tissue processing, IHC, IF, and antibody characterization.
• Strong analytical, troubleshooting, organizational, and communication skills.
• Thrives in a fast-paced environment.

Responsibilities

• Optimize tissue handling and processing protocols for protein staining (including FFPE samples).
• Design and execute experiments with novel imaging and biochemical platforms.
• Analyze and interpret data in collaboration with computational teams.
• Develop robust protocols for internal use across product development.

Skills

Spatial biology

Proteomics

Tissue imaging

In situ hybridization

Data analysis

Scientific communication

Education

PhD in Molecular/Cell Biology, Immunology, Biochemistry or related

Tools

Immunohistochemistry

Immunofluorescence

Antibody characterization

Job description

Role

Multidisciplinary scientist responsible for advancing spatial biology research and product development focused on high-plex tissue proteomics and biomolecule mapping within intact tissues.

Responsibilities

• optimize tissue handling and processing protocols for protein staining (including FFPE samples)
• design and execute experiments with novel imaging and biochemical platforms
• analyze and interpret data in collaboration with computational teams
• develop robust protocols for internal use across product development

Requirements

• PhD in Molecular/Cell Biology, Immunology, Biochemistry, or related field
• 5+ years of experience in proteomics, tissue imaging, in situ hybridization, and high-plex multiplexing technologies
• hands‑on expertise in tissue processing, immunohistochemistry, immunofluorescence, and antibody characterization
• strong analytical, troubleshooting, organizational, and communication skills
• ability to thrive in a fast‑paced environment

Preferred

• pathology experience
• proficiency in R
• Python
• AI coding
• image analysis

High-Value

• spatial multiomics
• tissue proteomics
• high-plex assays
• immunology
• cell biology
• biotech industry experience

Collaboration

Collaboration with cross-disciplinary teams including chemistry, computational biology, software, engineering, and microfluidics, reporting to R&D leadership.

Location

not specified, but environment suggests an innovative, collaborative setting.