Senior Scientist, Precision Oncology & CRISPR Innovation

Amgen SA

Thousand Oaks, Northern (CA, KY)

Hybrid

USD 120,000 - 180,000

Full time

7 days ago
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Benefits offered by this job

Total Rewards Plan
Stock-based incentives
Paid time off

Job summary

Amgen in Thousand Oaks seeks a Senior Scientist in Precision Oncology to shape experimental strategy for oncology programs and translate cancer biology into actionable drug discovery. You will collaborate with biology, chemistry, computational sciences, pharmacology, and translational teams to advance therapeutic hypotheses and drive program progression.

Ideal candidates have deep cancer biology expertise, strong experimental design, and a track record of solving complex biological problems in a

Qualifications

  • Doctorate or Master’s with 2+ years of scientific experience.
  • PhD in Cancer Biology preferred, with 1–3 years of postdoc/industry research.
  • Strong background in cancer cell biology and mechanistic pharmacology.

Responsibilities

  • Design and execute studies to validate oncology targets and define mechanisms of action.
  • Apply CRISPR genome editing to establish target function and dependencies.
  • Evaluate emerging technologies and AI tools to accelerate discovery.
  • Establish quantitative assays to investigate target engagement and pathway modulation.
  • Analyze complex data and communicate findings to multidisciplinary teams.
  • Collaborate with scientists across Research to advance oncology programs.

Skills

Cancer biology
Cell biology
Molecular biology
Genetics
Chemical biology
CRISPR editing
Imaging technologies

Education

PhD in Cancer Biology
Master’s degree +2 years
Bachelor’s degree +4 years

Tools

High-content imaging
Quantitative microscopy

Job description

Amgen in Thousand Oaks seeks a Senior Scientist in Precision Oncology to shape experimental strategy for oncology programs and translate cancer biology into actionable drug discovery. You will collaborate with biology, chemistry, computational sciences, pharmacology, and translational teams to advance therapeutic hypotheses and drive program progression.

Ideal candidates have deep cancer biology expertise, strong experimental design, and a track record of solving complex biological problems in a

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