Discovery Scientist, Rare Disease Biology

Amgen; Thousand Oaks (CA); Hybrid; USD 115,000 - 156,000; Full time

Job summary

Amgen in Thousand Oaks seeks a Scientist, Rare Disease Biology to advance discovery and progression of therapies for rare diseases. You will lead in vitro and ex vivo studies, develop human cellular disease models, including iPSC-based systems, and integrate data from genetics, literature, and clinical observations to inform portfolio decisions.

As a core member of multidisciplinary teams, you will balance rigorous science with urgency, contribute to target identification, and present findings

Qualifications

• PhD in Immunology, Neurology, Cell Biology, Molecular Biology, Pharmacology, Biomedical Sciences, or related field, OR Master's with 3+ years of research.
• Bachelor's with 5+ years of research experience.

Responsibilities

• Contribute to discovery and advancement of therapies for rare diseases using in vitro and ex vivo studies.
• Develop and apply human cellular models, including iPSC-based systems, to support discovery efforts.
• Integrate experimental findings with literature, genetics, and clinical observations to inform decisions.
• Collaborate with disease biologists, computational scientists, and translational researchers.
• Present findings to project teams and governance forums.

Skills

Neurobiology

Genetic disease biology

iPSC-derived models

CRISPR/Gene editing

Computational biology

Education

PhD in Immunology/Neurology/Cell Biology

Master's degree + 3 years research

Bachelor's degree + 5 years research

Tools

CRISPR tools

Organoid models

Job description

Amgen in Thousand Oaks seeks a Scientist, Rare Disease Biology to advance discovery and progression of therapies for rare diseases. You will lead in vitro and ex vivo studies, develop human cellular disease models, including iPSC-based systems, and integrate data from genetics, literature, and clinical observations to inform portfolio decisions.

As a core member of multidisciplinary teams, you will balance rigorous science with urgency, contribute to target identification, and present findings