Senior Scientist, NGS & Molecular Diagnostics Validation

Yoh,-A-Day-; Sunnyvale (CA); On-site; USD 160,000 - 220,000; Full time

Benefits offered by this job

Medical, Prescription, Dental & Vision

HSA

Life & Disability Insurance

401K

Direct Deposit

Certification opportunities

Job summary

Yoh, a Day & Zimmermann company, seeks a Senior Scientist to lead analytical validation for NGS and molecular diagnostics in Sunnyvale, CA. You will design validation studies, define acceptance criteria, and manage statistical analyses to ensure assay robustness and regulatory readiness.

Responsibilities cover cfDNA workflows, library preparation, data analysis, and collaboration with QA/regulatory teams. This full-time role emphasizes scientific leadership and rigorous documentation.

Qualifications

• Ph.D. in Molecular Biology or related field.
• Hands-on experience with cfDNA workflows and NGS library preparation.
• Experience designing analytical validation studies for molecular assays.
• Strong statistical design and data interpretation skills.
• Ability to work independently in regulated environments.

Responsibilities

• Design and execute analytical validation studies for molecular diagnostics.
• Develop study designs, acceptance criteria, and statistical plans.
• Lead LoB, LoD, LoQ and robustness evaluations.
• Perform NGS library prep and cfDNA workflows.
• Generate validation reports and technical summaries.

Skills

Molecular biology

NGS workflows

Analytical validation

Statistical analysis

Regulatory knowledge

Documentation

Cell-free nucleic acid

Education

Ph.D. in Molecular Biology/Genomics

Tools

R

Python

JMP

SAS

Job description

Yoh, a Day & Zimmermann company, seeks a Senior Scientist to lead analytical validation for NGS and molecular diagnostics in Sunnyvale, CA. You will design validation studies, define acceptance criteria, and manage statistical analyses to ensure assay robustness and regulatory readiness.

Responsibilities cover cfDNA workflows, library preparation, data analysis, and collaboration with QA/regulatory teams. This full-time role emphasizes scientific leadership and rigorous documentation.