Senior Scientist, Clinical Flow Cytometry Biomarkers

Bristol-Myers Squibb Co; Princeton (NJ); On-site; USD 124,000 - 150,000; Full time

Benefits offered by this job

Flexible Time Off

11 paid company holidays

Paid vacation 160 hours

Job summary

Bristol Myers Squibb is seeking a Senior Scientist in Princeton, NJ to lead flow cytometry biomarker assay design and validation for clinical development. The role involves hands‑on laboratory work, collaboration with cross‑functional teams, and mentoring junior scientists.

You will design experiments, optimize panels, analyze complex data, and determine whether to use internal or external labs, while maintaining rigorous documentation and quality standards.

Qualifications

• PhD, MS, or BSc in biological sciences, immunology, or related scientific discipline.
• Post‑graduate experience with flow cytometry (2+ years for PhD, 5+ years for MS, 7+ years for BSc), including high‑parameter work.
• Proven record of scientific contributions (publications, presentations, patents, or validated methods).
• Hands‑on expertise in high‑parameter flow cytometry assay design, instrument optimization, data analysis, and troubleshooting.
• Proficiency with FlowJo, FCS Express, OMIQ, or comparable analysis software.
• Working knowledge of fit‑for‑purpose qualification/validation of biomarker assays for clinical trials.
• Ability to write clear procedures, protocols, reports, and presentations; strong communication skills.

Responsibilities

• Lead design, development, optimization, qualification/validation, and execution of flow cytometry assays for clinical biomarker studies.
• Design experiments and select assay approaches aligned to program objectives and development stage.
• Apply panel design principles, reagent selection, instrument setup, and performance characterization.
• Perform or oversee clinical sample analysis to established quality standards.
• Decide on internal vs external laboratory use and oversee assay transfers.
• Evaluate and troubleshoot new flow cytometry methods and platforms.
• Interpret complex data and advise clinical/translational teams on next steps.
• Collaborate with cross-functional stakeholders on assay requirements, timelines, data delivery, and risk mitigation.
• Mentor junior scientists; author and review SOPs, validation protocols, and study documents.
• Maintain accurate records and promote scientific rigor and knowledge sharing.

Job description

Bristol Myers Squibb is seeking a Senior Scientist in Princeton, NJ to lead flow cytometry biomarker assay design and validation for clinical development. The role involves hands‑on laboratory work, collaboration with cross‑functional teams, and mentoring junior scientists.

You will design experiments, optimize panels, analyze complex data, and determine whether to use internal or external labs, while maintaining rigorous documentation and quality standards.