Senior Scientist, Clinical Flow Cytometry

Bristol-Myers Squibb Co; Princeton (NJ); On-site; USD 124,000 - 150,000; Full time

Benefits offered by this job

Flexible Time Off

11 paid company holidays

Paid vacation 160 hours

Job summary

Bristol Myers Squibb is seeking a Senior Scientist in Princeton, NJ to lead flow cytometry biomarker assay design and validation for clinical development. The role involves hands‑on laboratory work, collaboration with cross‑functional teams, and mentoring junior scientists.

You will design experiments, optimize panels, analyze complex data, and determine whether to use internal or external labs, while maintaining rigorous documentation and quality standards.

Qualifications

• PhD, MS, or BSc in biological sciences, immunology, or related scientific discipline.
• Post‑graduate experience with flow cytometry (2+ years for PhD, 5+ years for MS, 7+ years for BSc), including high‑parameter work.
• Proven record of scientific contributions (publications, presentations, patents, or validated methods).
• Hands‑on expertise in high‑parameter flow cytometry assay design, instrument optimization, data analysis, and troubleshooting.
• Proficiency with FlowJo, FCS Express, OMIQ, or comparable analysis software.
• Working knowledge of fit‑for‑purpose qualification/validation of biomarker assays for clinical trials.
• Ability to write clear procedures, protocols, reports, and presentations; strong communication skills.

Responsibilities

• Lead design, development, optimization, qualification/validation, and execution of flow cytometry assays for clinical biomarker studies.
• Design experiments and select assay approaches aligned to program objectives and development stage.
• Apply panel design principles, reagent selection, instrument setup, and performance characterization.
• Perform or oversee clinical sample analysis to established quality standards.
• Decide on internal vs external laboratory use and oversee assay transfers.
• Evaluate and troubleshoot new flow cytometry methods and platforms.
• Interpret complex data and advise clinical/translational teams on next steps.
• Collaborate with cross-functional stakeholders on assay requirements, timelines, data delivery, and risk mitigation.
• Mentor junior scientists; author and review SOPs, validation protocols, and study documents.
• Maintain accurate records and promote scientific rigor and knowledge sharing.

Job description

Position Summary

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it. Position Summary The Clinical Flow Cytometry team within Translational Sciences and Precision Medicine is seeking a Senior Scientist to develop and deliver flow cytometry-based biomarker assays supporting all phases of clinical development at BMS. Data from this team inform decisions on dose optimization, indication prioritization, patient selection, and potential drug combinations. In this laboratory-based role, the Senior Scientist will lead assay design, development, qualification/validation, and execution for assigned programs across therapeutic areas, lead or support assay transfer to external laboratories, and work independently on defined deliverables, with limited supervision on complex or novel challenges. The role serves as a technical point of contact, collaborates with cross‑functional stakeholders, and mentors junior scientists.

Key Responsibilities

• Lead the design, development, optimization, qualification/validation, and execution of novel, fit-for-purpose flow cytometry assays for clinical biomarker studies, with substantial hands‑on laboratory work.
• Design next experiments and recommend assay approaches suited to program objectives and stage of development.
• Apply sound principles of panel design, reagent selection, instrument setup, and performance characterization; refine protocols and methods as needed.
• Perform or oversee clinical sample analysis to established quality standards.
• Contribute to decisions on using internal laboratories, external laboratories, or both.
• Evaluate, implement, and troubleshoot new flow cytometry methods, technologies, and platforms.
• Analyze and interpret complex flow cytometry data and recommend next steps to clinical and translational teams.
• Serve as a technical point of contact for panel design, assay development, and data interpretation on assigned programs.
• Partner with cross‑functional stakeholders on assay requirements, endpoints, timelines, data delivery, and risk mitigation.
• Lead or support assay transfer to external laboratories, providing scientific oversight, troubleshooting, and quality review of their data.
• Manage concurrent assignments, prioritize for timely delivery, and elevate technical and operational risks as appropriate.
• Author and review method procedures, validation protocols and reports, study documentation, and technical summaries; present results in multidisciplinary meetings.
• Mentor and train junior scientists on assays, instruments, and procedures.
• Maintain accurate, traceable records and promote scientific rigor, collaboration, and knowledge sharing.

Minimum Requirements

• PhD, MS, or BSc in biological sciences, immunology, or related scientific discipline.
• At least 2 years of relevant post‑graduate experience with a PhD, 5 years with an MS, or 7 years with a BSc, including substantial flow cytometry work such as high‑parameter immunophenotyping, receptor occupancy, or functional assays.
• Record of scientific contribution, such as publications, presentations, patents, or validated methods.
• Strong hands‑on expertise in high‑parameter flow cytometry assay design, instrument optimization, data analysis, and troubleshooting.
• Proficiency with FlowJo, FCS Express, OMIQ, or comparable analysis software.
• Working knowledge of fit‑for‑purpose qualification and validation of biomarker assays for clinical trials.
• Ability to write clear, rigorous procedures, protocols, reports, and scientific presentations.
• Ability to manage multiple projects and deliver with limited supervision in a matrixed environment.
• Excellent communication, collaboration, organization, and record‑keeping skills.

Preferred Qualifications

• Biopharmaceutical industry experience
• Solid scientific knowledge of immunology
• Hands‑on experience with spectral or other high‑parameter flow cytometry platforms

Compensation Overview

Princeton - NJ - US: $123,670 - $149,855. The starting pay range(s) listed above is for full‑time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.

Benefits

• Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).
• U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year.
• Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.
• Depending on eligibility, employees may also have access to additional time‑off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs.
• Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.
• U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits

How We Work

Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site‑essential, site‑by‑design, field‑based and remote‑by‑design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

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Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. If this posting is missing required information required by local law or incorrect, contact BMS at [e-mail] the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.

R1607979 : Senior Scientist, Clinical Flow Cytometry Data Privacy Link

We’re creating innovative medicines for patients fighting serious diseases. We’re also nurturing our own diverse team with inspiring work and challenging career options. No matter the role, each one of us makes a contribution. And that makes all the difference.