Senior Scientist: Bioanalysis for Biologics & PK/PD

Prellis Biologics; Berkeley (CA); On-site; USD 150,000 - 210,000; Full time

Job summary

Prellis Biologics in Berkeley, CA is seeking a Scientist/Senior Scientist — Bioanalysis to develop bioanalytical assays (ELISA/LBA, LC-MS) for next-gen antibody modalities and support PK/PD in preclinical programs.

The role combines Protein Sciences, Analytical Development, and DMPK responsibilities and offers hands-on collaboration with cross-functional teams, with room to grow in a fast-paced biotech environment.

Qualifications

• Ph.D. or M.S. in a related field with industry exposure.
• Hands-on experience in bioanalytical assay development for biologics.
• Experience with ELISA/LBA, LC-MS/MS, LC-HRMS and related tech.
• Experience with PK/PD, serum/plasma bioanalysis and preclinical studies.
• Strong data interpretation and MS data workflow skills.

Responsibilities

• Lead bioanalytical method development for antibody modalities.
• Develop and optimize ELISA/LBA and MS-based assays.
• Analyze preclinical serum/plasma samples for PK/PD and exposure.
• Distinguish intact conjugates from degradation products in analyses.
• Collaborate across Protein Sciences, Analytical Development, DMPK and Pharmacology.
• Support assay qualification/validation and document high-quality data.

Skills

Bioanalytical assay development

ELISA/LBA

LC-MS/MS

PK/PD analysis

Data interpretation

MS data tools

Education

Ph.D. or M.S. in Bioanalytical Chemistry / Biochemistry / Biology / Pharmaceutical Sciences

Tools

Sciex Triple Quad

MS platforms (LC-MS/MS, LC-HRMS)

Laboratory automation (Hamilton / Tecan / Biomek)

Skyline / Analyst data analysis

Job description

Prellis Biologics in Berkeley, CA is seeking a Scientist/Senior Scientist — Bioanalysis to develop bioanalytical assays (ELISA/LBA, LC-MS) for next-gen antibody modalities and support PK/PD in preclinical programs.

The role combines Protein Sciences, Analytical Development, and DMPK responsibilities and offers hands-on collaboration with cross-functional teams, with room to grow in a fast-paced biotech environment.