Senior Scientist, Analytical Dev & QC (Nucleic Acids)

Flagship Pioneering; Cambridge (MA); On-site; USD 109,000 - 182,000; Full time

Job summary

Serif Biomedicines in Cambridge, MA, is seeking a Senior Scientist for Analytical Development and Quality Control to lead method development for nucleic acid therapeutics and LNP delivery platforms. This role requires hands-on benchwork, scientific rigor, and mentorship within a fast-paced entrepreneurial team.

The candidate will guide development projects, contribute to regulatory filings, and collaborate across cross-functional teams to advance analytical capabilities and product

Responsibilities

• Lead method development and implementation to support nucleic acid cargo and LNP product release, stability and characterization
• Lead experimental studies to optimize specificity, sensitivity, precision, accuracy, and/or linearity of analytical methods
• Troubleshoot assay development and instrument operation issues, serving as a technical resource for the broader team
• Experimental planning, study design and scheduling of development projects as well as routine testing across programs
• Support day-to-day execution of analytical analysis for process development activities to ensure robust process and product characterization
• Work independently and collaboratively in a multidisciplinary team environment, providing technical guidance and mentorship to junior colleagues
• Analyze, troubleshoot, and communicate experimental findings clearly and succinctly in oral, written, and visual formats to internal teams and cross-functional stakeholders
• Provide technical input to support regulatory filings
• Author and manage protocols, laboratory data, and technical reports

Job description

Serif Biomedicines in Cambridge, MA, is seeking a Senior Scientist for Analytical Development and Quality Control to lead method development for nucleic acid therapeutics and LNP delivery platforms. This role requires hands-on benchwork, scientific rigor, and mentorship within a fast-paced entrepreneurial team.

The candidate will guide development projects, contribute to regulatory filings, and collaborate across cross-functional teams to advance analytical capabilities and product