Researcher

Mindlance; Worcester (MA); On-site; USD 80,000 - 100,000; Full time

Job summary

Mindlance is seeking a motivated scientist for the Biologics CMC Developability team in Worcester, MA. The successful candidate will perform characterization using LC-MS and contribute to biologic drug development.

The role requires expertise in biopharmaceuticals, collaboration skills, and a strong educational background in relevant fields. This is a contractor position with potential extensions based on performance.

Qualifications

• BS or MS in Biochemistry, Biology, Chemistry, or equivalent, with experience in biopharmaceuticals.
• 5+ years (BS) or 2+ years (MS) or Ph.D. with no experience.
• Hands-on experience with protein mass-spectrometry and data processing.

Responsibilities

• Perform in-depth LC-MS characterization of therapeutic biologic molecules.
• Conduct liquid chromatography characterization of biologic drug candidates.
• Prepare and deliver concise scientific presentations of experimental results.

Skills

Biologics characterization using liquid chromatography- mass spectrometry (LC-MS)

Hands-on experience with protein mass-spectrometry

Experience with liquid chromatography methods

Ability to use MS Excel & GraphPad for data analysis

Excellent collaboration and communication skills

Education

BS or MS in Biochemistry, Biology, Chemistry, or equivalent

Ph.D. with biopharmaceutical industry experience

Tools

Liquid handling robots

Job description

Contract: 12+ months - possible extension - based on performance and business needs

What are the top 3-5 skills, experience or education required for this position:

• Biologics characterization using liquid chromatography- mass spectrometry (LC-MS).
• BS or MS in Biochemistry, Biology, Chemistry (or equivalent, e.g., Chemical Engineering, Pharmaceutical Sciences) with 5+ (BS) or 2+ years (MS), or Ph.D. with 0+ years of biopharmaceutical industry experience.

Contractor position – Biologics Developability

The Biologics CMC Developability team is an integral part of the Biologics CMC Drug Product Development Org. The Biologics CMC Developability team is responsible for- (1) the identification of biophysical- and chemical liabilities in discovery-stage biologic drug candidates to guide lead selection, and (2) for characterization of the key CMC attributes important for biologic drug development. We have an exciting opportunity for a motivated scientist to join the Biologics CMC Developability team.

Key Responsibilities

• Perform in-depth LC-MS based characterization of therapeutic biologic molecules and their post-translational modifications.
• Conduct liquid chromatography-based characterization of biologic drug candidates (size exclusion, ion exchange, and reverse phase).
• Execute experimental protocols, collect results, and perform data analysis carefully and independently.
• Maintain excellent documentation of work including electronic lab notebook and protocols.
• Prepare and deliver concise scientific presentations of experimental results.
• Oversee maintenance of key laboratory equipment and routine laboratory operations.
• Build strong relationships with other team members and across groups.
• Understand and adhere to corporate standards regarding code of conduct, safety, and documentation compliance.

Qualifications

• BS or MS in Biochemistry, Biology, Chemistry (or equivalent, e.g., Chemical Engineering, Pharmaceutical Sciences) with 5+ (BS) or 2+ years (MS), or Ph.D. with 0+ years of biopharmaceutical industry experience.
• Hands‑on experience with protein mass‑spectrometry (subunit analysis, peptide mapping, disulfide mapping) and data processing is required.
• Experience with liquid chromatography methods commonly used for characterization of biologic proteins is required.
• Experience with liquid handling robots and their programming would be highly beneficial.
• Demonstrated track record of independent thinking, creativity, and scientific accomplishment.
• Highly responsible and self‑motivated. Skills to plan and conduct experiments with high quality and timely deliverables. Able to perform data analysis using MS Excel & GraphPad.
• Team player with excellent collaboration and communication skills.

EEO

“Mindlance is an Equal Opportunity Employer and does not discriminate in employment on the basis of – Minority/Gender/Disability/Religion/LGBTQI/Age/Veterans.”