Associate Scientist, Biologics Analytics & Characterization

ProtaGene, GmbH; Burlington, Northern (MA, KY); Hybrid; USD 90,000 - 120,000; Full time

Benefits offered by this job

Paid time off

Medical/dental/vision insurance

401(k)

Job summary

ProtaGene, GmbH in the United States seeks an Associate Scientist / Scientist in Analytical Sciences to perform physicochemical and biochemical characterization of biologics using HPLC/UPLC, IEF, CE, spectroscopy, and binding/kinetic assays. You will design experiments, analyze data, and communicate results while maintaining GLP-like records and collaborating across teams.

The role requires hands-on CRO/QC experience, strong software skills (Waters Empower), and an ability to manage multiple

Qualifications

• Master’s or bachelor’s degree in chemistry, Biochemistry, or a related scientific discipline with 2-5 years (MSc.) or 4-6 years (BSc.) of relevant industry experience.
• Demonstrated hands-on experience with analytical characterization techniques, particularly chromatography (U/HPLC), electrophoretic and isoelectric focusing (PA 800 Plus/Maurice), is required.
• Experience working in a CRO and/or GMP Quality Control (QC) environment is highly desirable.
• Proficiency with Waters Empower™ chromatography data software is a strong plus.
• Working knowledge of biotherapeutic analytical development (e.g., method qualification and/or validation and assay transfer).
• Experience with additional biophysical characterization techniques, such as SEC-MALS, DSC, circular dichroism (CD), FT-IR, or MFI, and/or LC-MS-based characterization of biotherapeutics is highly desirable but not required.
• Ability to independently plan and execute experiments while managing multiple priorities and maintaining timelines in a fast-paced environment.
• Ability to work successfully in both a team/matrix environment as well as independently.
• Experience with the analytical characterization of oligonucleotides a plus.

Responsibilities

• Perform physicochemical and biochemical characterization of biologics using techniques such as HPLC/UPLC, IEF, CE, spectroscopy, biochemical assays, and binding/kinetic assays.
• Independently design and execute laboratory studies, analyze data, troubleshoot, and communicate findings via reports, presentations, and team discussions.
• Prepare and maintain assay reagents, reference standards, controls, and materials for analytical testing activities.
• Maintain accurate laboratory records, ELNs, and protocols in line with company procedures and quality standards.
• Collaborate with multidisciplinary teams to ensure timely delivery of analytical results and project milestones.

Skills

HPLC/UPLC

IEF

Capillary electrophoresis

Spectroscopy

Biochemical assays

Binding/kinetic assays

Education

Bachelor's or Master's in Chemistry/Biochemistry

Tools

Waters Empower

Job description

ProtaGene, GmbH in the United States seeks an Associate Scientist / Scientist in Analytical Sciences to perform physicochemical and biochemical characterization of biologics using HPLC/UPLC, IEF, CE, spectroscopy, and binding/kinetic assays. You will design experiments, analyze data, and communicate results while maintaining GLP-like records and collaborating across teams.

The role requires hands-on CRO/QC experience, strong software skills (Waters Empower), and an ability to manage multiple