Senior Scientist

Scorpion Therapeutics; Lebanon (NH); On-site; USD 120,000 - 180,000; Full time

Job summary

Scorpion Therapeutics seeks a lead scientist to design and optimize affinity chromatography technologies for diverse biopharmaceutical modalities, aiming to advance bioprocessing performance and partner success.

You will conduct high-throughput experiments, apply DOE, analyze complex datasets, and collaborate with chemistry, analytics, and commercial teams to drive multiple programs with quality and timeliness.

Qualifications

• MS or PhD in Biochemistry, Chemical Engineering, or related field.
• 5+ years' experience in downstream processing, protein purification, and chromatography (including FPLC).
• Expertise across modalities such as proteins, enzymes, vaccines, VLPs, or gene therapy vectors.
• Strong skills in chromatography method development, automated/high-throughput systems, and DOE.

Responsibilities

• Lead design and optimization of affinity chromatography for diverse biopharma modalities.
• Conduct high-throughput experimentation and apply DOE for process development.
• Analyze complex datasets to inform decision-making.
• Collaborate cross-functionally with chemistry, analytics, and commercial teams.
• Contribute to multiple development programs ensuring quality and timeliness.
• Propose innovative purification approaches and engage with external partners as expert.

Skills

Chromatography method development

High-throughput screening

DOE methodologies

Data analysis

Communication skills

Education

MS or PhD in Biochemistry, Chemical Engineering, or related field

Tools

FPLC

Automated/high-throughput systems

Job description

Role

Lead design and optimization of affinity chromatography technologies for diverse biopharmaceutical modalities, focusing on advancing bioprocessing performance and partner success.

Responsibilities

• conduct high-throughput experimentation
• apply DOE methodologies for process development
• analyze complex datasets to inform decision-making
• collaborate cross-functionally with chemistry, analytics, and commercial teams
• contribute to multiple development programs ensuring quality and timeliness
• propose innovative purification approaches
• engage with external biopharma partners as a scientific expert

Qualifications

• MS or PhD in Biochemistry, Chemical Engineering, or related field;
• at least 5 years' experience in downstream processing, protein purification, and chromatography (including FPLC);
• expertise in multiple modalities such as proteins, enzymes, vaccines, VLPs, or gene therapy vectors;
• strong skills in chromatography method development, automated/high-throughput systems, and DOE;
• working knowledge of analytical techniques for purity, potency, and stability;
• broad understanding of bioprocessing and protein chemistry;
• excellent communication skills.

High-Value

affinity chromatography, process development, high-throughput screening, DOE, bioprocessing, multiple modalities, external collaboration.

Work Setup

not specified; likely collaborative, fast-paced environment.