Process Development Senior Scientist

Insight Global; King of Prussia (PA); On-site; USD 120,000 - 135,000; Full time

Benefits offered by this job

Performance-based bonus

Defined benefit pension plan

Comprehensive benefit packages

Job summary

A bioprocessing client is seeking a Senior Scientist in King of Prussia, PA. This role is fully on site and entails leading downstream process development, specifically chromatographic purification of monoclonal antibodies. The ideal candidate should possess a strong background in biochemistry, including extensive hands-on experience and the ability to manage a small team. Key responsibilities include designing purification processes and guiding development efforts to assist biopharmaceutical companies in delivering therapies efficiently.

Qualifications

• 8 years of relevant industry experience with M.S., or 5 years with Ph.D.
• Proven ability to lead small scientific teams and manage lab operations.
• Hands-on experience with chromatography techniques.

Responsibilities

• Design, execute, and analyze chromatography-based purification processes.
• Develop scalable purification processes tailored to client molecules.
• Lead technology transfer activities to external manufacturing sites.

Skills

Downstream process development

Preparative chromatography

Antibody purification

Leadership

Analytical techniques

Education

M.S. in Biochemistry, Chemical Engineering, Biotechnology, or related field

Ph.D.

Tools

AKTA systems

Unicorn software

HPLC

Job description

Base pay range

$120,000.00/yr - $135,000.00/yr

Details of the Role

• $120,000-$135,000 annually - exact rate is based on several factors, including skills, experience, and education.
• 15% performance based bonus annually
• After 3 years tenure, we offer a robust defined benefit pension plan
• Shift: Mon-Fri 7am-4:30pm core working hours
• Benefit packages for this role will start on the 1st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law

Required Skills & Experience

• M.S. in Biochemistry, Chemical Engineering, Biotechnology, or related field with 8 years of relevant industry experience, OR
• Ph.D. with 5 years of experience in downstream process development for biologics.
• Demonstrated expertise in preparative chromatography and antibody purification.
• Proven ability to lead small scientific teams and manage lab operations.

Nice to Have Skills & Experience

• Hands-on experience with AKTA systems, Unicorn software, and high-throughput screening platforms (e.g., Tecan Te-Chrom).
• Proficiency in analytical techniques such as HPLC, SDS-PAGE, ELISA, UV spectroscopy.
• Familiarity with tech transfer, cGMP/cGLP standards, and regulatory documentation. Experience in client-facing or CDMO environments is a plus.

Job Description

One of our large bioprocessing clients is seeking a Senior Scientist to join their R&D team in King of Prussia, PA. This role is fully on site, 5 days/week and will lead downstream process development efforts focused on the chromatographic purification of monoclonal antibodies. This role is central to our clients mission of enabling large and small biopharmaceutical companies to bring transformative therapies to patients faster and more efficiently. This individual will guide a small team (6 reports max) in designing and executing purification strategies that support late-stage development and manufacturing readiness. This role will be 50% hands on bioprocess development and 50% people managing. Some responsibilities include but are not limited to:

• Design, execute, and analyze chromatography-based purification processes (Protein A, ion exchange, HIC, etc.) for mAbs.
• Develop scalable, robust purification processes tailored to client molecules and manufacturing goals.
• Lead technology transfer activities to external manufacturing sites.
• Author technical reports, protocols, and support regulatory documentation.

Seniority level

Mid-Senior level

Employment type

Full-time

Job function

Science

Industries

Pharmaceutical Manufacturing