Senior Translational PK/PD Scientist - Model-Informed Decisions

Scorpion Therapeutics

Boston (MA)

On-site

USD 129,000 - 203,000

Full time

14 days+

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Benefits offered by this job

Annual bonus

Medical/dental/vision insurance

401(k) retirement plan

Job summary

Scorpion Therapeutics in Boston seeks a Translational PK/PD Senior Scientist to drive model-informed decisions across drug discovery and dose prediction. The role integrates PKPD modeling with experimental data, supporting forward and reverse translation and informing modality selection.

You will build PKPD, PBPK, and QSP platforms, design studies, and contribute to automated workflows. Collaboration with multidisciplinary teams will advance candidate optimization and human dose projection

Qualifications

Education: Master’s (3+ years), PharmD (1 year), or Ph.D. in pharmacokinetics/pharmacodynamics, mathematics, applied mathematics, systems/computational biology, chemical/biomedical engineering, statistics/biostatistics, or related field.
Hands-on translational PKPD modeling using standard software (e.g., Matlab, OSP Suite, Monolix, R).
Strong experimental design, mathematical problem solving, critical data analysis/interpretation, and/or statistics.

Responsibilities

Serve as PK/PD modeler in cross-functional teams to support model-informed decisions on drug discovery, modality selection, and dose prediction.
Integrate in vitro and in vivo data to build PKPD, PBPK, QSP, and other mechanistic modeling platforms to support forward/reverse translation.
Collaborate to design experimental studies and modeling plans to identify and optimize drug candidates.
Collaborate on automated workflows for implementing modeling platforms to inform human PK/PD and dose projections.
Build expertise and leadership in translational modeling and drug discovery (with guidance from experienced modelers).