Senior Process Engineer, Oligonucleotide API

Biopharma Careers; Houston, Northern (TX, KY); Hybrid; USD 110,000 - 160,000; Full time

Job summary

Lilly in Houston is seeking a Senior Process Engineer for oligonucleotide API manufacturing. You will serve as front-line engineer, support qualification, process safety, and continuous improvement in a new GMP facility startup planned for 2029–2030.

Role emphasizes cross-functional collaboration with production, science, and engineering teams, data-driven decisions, and scalable process design for phase-appropriate operations.

Qualifications

• Bachelor's degree in Chemical, Biochemical, or Mechanical Engineering or related STEM field.
• 3+ years of GMP manufacturing experience.
• Experience with oligonucleotide or API processes is a plus.

Responsibilities

• Serve as front-line process engineer for oligonucleotide API operations.
• Support equipment qualification, process documentation, and risk assessments.
• Contribute to process optimization, data analysis, and tech transfer during startup.

Skills

Oligonucleotide API

GMP manufacturing

Process Safety

Data analysis

Tech transfer

Cross-functional

Root cause

Education

Bachelors in Engineering

Tools

Process simulation

Job description

Lilly in Houston is seeking a Senior Process Engineer for oligonucleotide API manufacturing. You will serve as front-line engineer, support qualification, process safety, and continuous improvement in a new GMP facility startup planned for 2029–2030.

Role emphasizes cross-functional collaboration with production, science, and engineering teams, data-driven decisions, and scalable process design for phase-appropriate operations.