Senior Process Engineer — Foundry Scale-Up Leader

BioSpace; Lebanon (IN); On-site; USD 129,000 - 189,000; Full time

Benefits offered by this job

Annual bonus

401(k) plan

Health benefits

Job summary

Lilly’s Medicine Foundry is seeking an Advisor – Process Engineer to lead scale-up and manufacturing support for small molecule APIs. You will provide expert engineering guidance across development to GMP manufacturing, shaping processes, equipment, and the engineering culture for a greenfield site.

This senior role requires advanced chemical engineering expertise, leadership, and strong collaboration with HSE, QA, Operations, and Development to ensure safe, compliant, and efficient production.

Qualifications

• PhD in Chemical Engineering, Chemistry, Pharmaceutical Sciences, or a related discipline.
• B.S. or M.S. in Chemical Engineering or a related discipline with 10+ years of experience in pharmaceutical, biotech, or CMO process engineering supporting drug substance API development or manufacturing.

Responsibilities

• Understand and comply with GMP, safety and applicable regulations, and support Foundry Quality systems.
• Serve as Technical Authority for Equipment Design and Scale-up across small molecule node.
• Lead heat and mass transfer modeling and reactor sizing for scale-up to kilo lab and pilot plant.
• Guide reactor selection for batch, semi-batch, continuous flow, and high-pressure systems.
• Lead P&ID reviews and communicate design intent across disciplines and vendors.
• Develop and maintain manufacturing processes and control strategies for APIs.
• Assist in regulatory submissions and IND/CTP documentation preparations.
• Author technical reports and design basis documents with proper notebooks.

Skills

Chemical engineering fundamentals

Process development

Scale-up expertise

Project management

Leadership

Education

PhD in Chemical Engineering or related

B.S./M.S. in Chemical Engineering or related with 10+ years experience

Tools

DynoChem

Aspen

DeltaV

Job description

Lilly’s Medicine Foundry is seeking an Advisor – Process Engineer to lead scale-up and manufacturing support for small molecule APIs. You will provide expert engineering guidance across development to GMP manufacturing, shaping processes, equipment, and the engineering culture for a greenfield site.

This senior role requires advanced chemical engineering expertise, leadership, and strong collaboration with HSE, QA, Operations, and Development to ensure safe, compliant, and efficient production.