Senior Process Development Scientist: Protein Purification

Curia Aalborg ApS; Hopkinton (MA); On-site; USD 114,000 - 146,000; Full time

Benefits offered by this job

Generous benefits

Paid training

Career advancement

Education reimbursement

401k program

Learning platform

And more

Job summary

Curia in Hopkinton, MA is seeking a Senior Research Scientist I for Process Development to lead purification schemes for protein-based technologies and advance downstream capabilities. You will balance multiple projects, prioritize tasks to meet timelines, and mentor staff while collaborating with management.

The role requires extensive hands-on purification experience, strong analytical problem solving, and ability to transfer methods to CMOs in a fast-paced environment.

Qualifications

• Bachelor's degree in Biology, Biochemistry, Chemical Engineering or related field.
• Minimum 9-13 years' direct hands-on experience with protein purification techniques such as chromatography and tangential flow filtration.
• Master's degree in Biology, Biochemistry, Chemical Engineering or related field with 7-11 years' experience.
• PhD in Biology, Biochemistry, Chemical Engineering or related field with 4-8 years' experience.

Responsibilities

• Develop protein purification schemes for antibodies and biospecifics.
• Independently investigate analytical results and provide robust solutions.
• Review literature to generate purification scheme proposals.
• Analyze, interpret, and present results in summaries.
• Generate and follow SOPs for cGMP production of material.
• Maintain laboratory instruments.
• Document results in lab notebooks and batch records.
• Follow SOPs for mammalian cell culture and protein/antibody purification.
• Optimize methods and facilitate tech transfer to CMOs.
• Think critically and creatively to troubleshoot process development issues.
• Work independently and collaboratively to complete projects.
• Mentor and supervise staff and collaborate with management teams.

Skills

Protein purification

DOE analysis

Cross-functional teamwork

Communication

Mentoring staff

Education

Bachelor's degree (Biology/Biochemistry/Chemical Engineering)

Master's degree

PhD

Tools

FPLC systems

Affinity chromatography

Ion exchange chromatography

Tangential flow filtration

Job description

Curia in Hopkinton, MA is seeking a Senior Research Scientist I for Process Development to lead purification schemes for protein-based technologies and advance downstream capabilities. You will balance multiple projects, prioritize tasks to meet timelines, and mentor staff while collaborating with management.

The role requires extensive hands-on purification experience, strong analytical problem solving, and ability to transfer methods to CMOs in a fast-paced environment.