Senior Research Scientist I; Process Development Science

Curia; Hopkinton (MA); On-site; USD 114,000 - 146,000; Full time

Benefits offered by this job

Generous benefits

Paid training

Career advancement

Education reimbursement

401k program

Learning platform

And more

Job summary

Curia in Hopkinton, MA is seeking a Senior Research Scientist I for Process Development to lead purification schemes for protein-based technologies and advance downstream capabilities. You will balance multiple projects, prioritize tasks to meet timelines, and mentor staff while collaborating with management.

The role requires extensive hands-on purification experience, strong analytical problem solving, and ability to transfer methods to CMOs in a fast-paced environment.

Qualifications

• Bachelor's degree in Biology, Biochemistry, Chemical Engineering or related field.
• Minimum 9-13 years' direct hands-on experience with protein purification techniques such as chromatography and tangential flow filtration.
• Master's degree in Biology, Biochemistry, Chemical Engineering or related field with 7-11 years' experience.
• PhD in Biology, Biochemistry, Chemical Engineering or related field with 4-8 years' experience.

Responsibilities

• Develop protein purification schemes for antibodies and biospecifics.
• Independently investigate analytical results and provide robust solutions.
• Review literature to generate purification scheme proposals.
• Analyze, interpret, and present results in summaries.
• Generate and follow SOPs for cGMP production of material.
• Maintain laboratory instruments.
• Document results in lab notebooks and batch records.
• Follow SOPs for mammalian cell culture and protein/antibody purification.
• Optimize methods and facilitate tech transfer to CMOs.
• Think critically and creatively to troubleshoot process development issues.
• Work independently and collaboratively to complete projects.
• Mentor and supervise staff and collaborate with management teams.

Skills

Protein purification

DOE analysis

Cross-functional teamwork

Communication

Mentoring staff

Education

Bachelor's degree (Biology/Biochemistry/Chemical Engineering)

Master's degree

PhD

Tools

FPLC systems

Affinity chromatography

Ion exchange chromatography

Tangential flow filtration

Job description

Job Description

Senior Research Scientist I; Process Development in Hopkinton, MA Build your future at Curia, where our work has the power to save lives.

Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives.

We proudly offer

• Generous benefit options (eligible first day of employment)
• Paid training, vacation and holidays (vacation accrual begins on first day of employment)
• Career advancement opportunities
• Education reimbursement
• 401k program
• Learning platform
• And more!

Position Overview

The Senior Research Scientist I, Process Development Science steers development programs for cutting edge protein-based technologies. The Senior Research Scientist must be able to handle multiple projects at a time, prioritize tasks to meet timelines, and thrive in a fast-paced environment. This role is responsible for developing purification schemes for a wide class of protein-based technologies and contribute to expanding the downstream process capabilities of the team.

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Supervisory Responsibilities

This position may have supervisory responsibilities.

Essential Job Duties

• Develop protein purification schemes for a wide class of protein-based technologies including antibodies and biospecifics
• Independently investigate complex analytical results and provide robust solutions
• Review literature to generate purification scheme proposals
• Analyze, interpret, and clearly present results in result summaries
• Generate and follow SOPs for cGMP production of material
• Maintain laboratory instruments
• Document results in lab notebooks and batch records
• Follow SOPs for mammalian cell culture and protein/antibody purification
• Optimize methods and facilitate tech transfer to CMOs
• Think critically and creatively to troubleshoot issues related to process development
• Work independently and collaboratively to complete projects
• Mentor and supervise staff as well as work effectively with management teams

Education, Experience, Certification And Licensures

• Bachelor's degree in Biology, Biochemistry, Chemical Engineering or related field
• Minimum 9-13 years' direct hands-on experience with protein purification techniques such as chromatography and tangential flow filtration

OR

• Master's degree in Biology, Biochemistry, Chemical Engineering or related field
• Minimum 7-11 years' direct hands-on experience with protein purification techniques such as chromatography and tangential flow filtration

OR

• PhD in Biology, Biochemistry, Chemical Engineering or related field
• Minimum 4-8 years' direct hands-on experience with protein purification techniques such as chromatography and tangential flow filtration

Knowledge, Skills And Abilities

• Apply scientific principles and personal experience to design and execute experiments to solve problems
• Proficient in protein purification using affinity, ion exchange, and hydrophobic interaction chromatography with FPLC systems
• Working knowledge of experimental design and data analysis using Design of Experiments (DOE) is a plus
• Ability to prioritize responsibilities, multi-task, and remain flexible with changing needs
• Must be motivated and able to work under tight deadlines
• Excellent interpersonal and oral and written communication interpersonal
• Good documentation and organization
• Ability to work effectively in cross functional teams to solve process development problems or implement improved procedures

Other Qualifications

• Must pass a background check
• Must pass a drug screen
• May be required to pass Occupational Health Screening

Physical Requirements

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

The employee is frequently required to stand; walk; sit; use hands to finger, handle, or feel and reach with hands and arms. Light to moderate lifting and carrying objects with a maximum lift of 30lbs. Must be able to work while wearing personal protective equipment such as safety glasses, gloves, and lab coats deemed necessary to protect testing and to protect employees.

Work Environment

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Work is performed in an office and laboratory environment. May be exposed to biological and chemical hazards.

Salary Range: $113,700-145,800

Education, experience, location and tenure may be considered along with internal equity when job offers are extended.

Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.