Senior Principal Toxicologist & Translational Safety Leader

Genentech; San Francisco (CA); On-site; USD 173,000 - 322,000; Full time

Benefits offered by this job

Relocation benefits

Job summary

Genentech, located in South San Francisco, seeks a Senior Principal Scientist in Translational Safety to provide scientific leadership across drug development, from discovery through clinical development and marketed products. You will integrate toxicology, pathology, pharmacology, translational, and clinical data to shape strategy and enable timely decisions.

You will lead cross-functional teams, design safety programs, mentor scientists, and contribute to regulatory strategy and external

Qualifications

• PhD in toxicology or related field required with substantial industry experience.
• Proven ability to interpret nonclinical safety data and inform translational decisions.
• Experience interacting with global regulatory authorities and leading risk assessments.

Responsibilities

• Lead safety assessment of Genentech therapeutics with weight-of-evidence approaches.
• Design and implement safety programs for GLP/non-GLP studies to answer key questions.
• Collaborate with pathologists, translators, pharmacology, clinicians and regulatory colleagues.

Skills

Decision making

Data analysis

Verbal communication

Written communication

Cross-functional collaboration

Regulatory interactions

Scientific leadership

Education

PhD in toxicology or relevant field

Post-doctorate or equivalent experience

Job description

Genentech, located in South San Francisco, seeks a Senior Principal Scientist in Translational Safety to provide scientific leadership across drug development, from discovery through clinical development and marketed products. You will integrate toxicology, pathology, pharmacology, translational, and clinical data to shape strategy and enable timely decisions.

You will lead cross-functional teams, design safety programs, mentor scientists, and contribute to regulatory strategy and external