Lead Translational Toxicologist - Safety Strategy Leader

Genentech; South San Francisco (CA); On-site; USD 142,000 - 263,000; Full time

Job summary

Genentech is seeking a Principal Scientist in Translational Safety located in South San Francisco. The role focuses on providing scientific leadership across drug development, leading safety assessments, and shaping strategies for multiple development programs, including novel modalities.

You will design safety programs, integrate toxicology, pathology, pharmacology, and clinical data, and communicate risk assessments to senior decision-makers, contributing to portfolio strategy.

Qualifications

• PhD and post-doctorate or equivalent experience in toxicology with 3+ years in pharma/biotech/CRO.
• Strong decision making, problem solving and data interpretation are required.
• Experience communicating with global regulatory authorities is desirable.

Responsibilities

• Lead safety assessment of Genentech therapeutics across programs.
• Design and oversee GLP and non-GLP safety studies to support development milestones.
• Synthesize data and literature to form weight-of-evidence risk assessments.

Skills

Decision making

Problem solving

Data analysis

Communication

Education

PhD or equivalent in toxicology

Job description

Genentech is seeking a Principal Scientist in Translational Safety located in South San Francisco. The role focuses on providing scientific leadership across drug development, leading safety assessments, and shaping strategies for multiple development programs, including novel modalities.

You will design safety programs, integrate toxicology, pathology, pharmacology, and clinical data, and communicate risk assessments to senior decision-makers, contributing to portfolio strategy.