Senior PMO Leader - IT Delivery & Governance

Medpace; Cincinnati (OH); Hybrid; USD 140,000 - 190,000; Full time

Benefits offered by this job

Health benefits

Retirement plan

Paid time off

Job summary

Medpace seeks a strategic and hands-on PMO Leader to build and run the IT PMO. You will mentor IT Project Managers, define governance, and ensure regulatory alignment across Agile, Waterfall, and hybrid software delivery environments.

The role partners with IT leadership and business stakeholders to optimize the project portfolio, improve delivery performance, and drive continuous improvement within a CRO-focused organization.

Qualifications

• Bachelor's degree in Information Technology, Computer Science, Business Administration, or related field (Master's degree preferred).
• 10+ years of experience in IT project management, including 3+ years in a leadership role managing project managers or a PMO.
• Demonstrated experience establishing or maturing PMO processes, governance frameworks, and project standards.
• Strong knowledge of software development lifecycle (SDLC) methodologies, including Agile, Waterfall, and hybrid approaches.
• Experience managing a portfolio of concurrent software projects, including budgets, resource planning, and risk management.
• Proven ability to communicate effectively with executives, business stakeholders, and technical teams.
• Strong leadership, coaching, and conflict resolution skills.
• Proficiency with project and portfolio management tools and reporting platforms.

Responsibilities

• Lead, mentor, and develop a team of IT Project Managers, including hiring, performance management, and career development.
• Allocate PM resources across projects based on priorities, complexity, and team capacity.
• Foster a culture of accountability, continuous improvement, and collaboration between project management and engineering teams.
• Establish, document, and maintain project management methodologies, standards, templates, and best practices (Agile, Waterfall, and hybrid approaches).
• Define and enforce project governance, including stage gates, approval processes, change control, and escalation paths.
• Ensure software development projects meet regulatory, quality, and data integrity requirements applicable to a CRO environment (e.g., GxP, 21 CFR Part 11, validation requirements).
• Partner with Validation and Quality Assurance teams to align PMO processes with SDLC, computer system validation, and audit-readiness expectations.
• Conduct periodic project health checks and audits to confirm adherence to PMO standards.
• Own the IT project portfolio, including intake, prioritization, and roadmap planning in collaboration with IT and business leadership.
• Develop and deliver portfolio dashboards, status reports, and key performance metrics to senior leadership.
• Oversee portfolio-level resource forecasting and capacity planning.
• Identify cross-project dependencies, risks, and conflicts, and drive resolution at the portfolio level.
• Define PMO strategy, goals, and maturity roadmap aligned with IT and corporate objectives.
• Select, implement, and administer project and portfolio management tools (e.g., Jira, Azure DevOps, Smartsheet, Microsoft Project).
• Lead post-project reviews and use lessons learned to refine processes and improve delivery outcomes.
• Serve as an escalation point for high-risk or high-visibility projects and provide direct project oversight when needed.

Skills

Leadership

PMO management

SDLC knowledge

Agile/Waterfall hybrid

Portfolio management

Risk management

Executive communication

Resource planning

Education

Bachelor's degree in IT/CS/Business

Master's degree preferred

Tools

Jira

Azure DevOps

Smartsheet

Microsoft Project

Power BI

Job description

Medpace seeks a strategic and hands-on PMO Leader to build and run the IT PMO. You will mentor IT Project Managers, define governance, and ensure regulatory alignment across Agile, Waterfall, and hybrid software delivery environments.

The role partners with IT leadership and business stakeholders to optimize the project portfolio, improve delivery performance, and drive continuous improvement within a CRO-focused organization.