Senior Molecular Biodistribution Scientist

AskBio Inc.; Durham (NC); On-site; USD 110,000 - 150,000; Full time

Job summary

AskBio Inc. in RTP, NC is seeking a Senior Research Associate, Molecular Biodistribution to execute biodistribution and gene expression assays. You will generate high-quality data and interpret results to guide candidate selection, dose strategy, and safety assessment for regulatory submissions.

The role requires hands-on assay development, data analysis, and cross-functional collaboration with Product Development Cores and other teams. Onsite in RTP, NC.

Qualifications

• Bachelor’s or Master’s degree in a related scientific discipline with relevant work experience.
• Experience in biotech/pharma or academic settings supporting genetic medicine.
• Direct experience with biodistribution and gene expression studies for gene therapy (AAV).
• Hands-on nucleic acid extraction from tissues and biofluids and with quantitative molecular assays.
• Experience supporting preclinical development and regulated documentation.
• Understanding nonclinical development considerations for genetic medicines.

Responsibilities

• Develop and execute biodistribution and gene expression experiments.
• Quantify vector genomes and transgene expression in tissues and fluids.
• Analyze datasets and interpret results to inform candidate selection and dose strategy.
• Collaborate with cross-functional teams for study design and data interpretation.
• Prepare summaries for reports and regulatory documentation.

Skills

Molecular biology

AAV gene therapy

qPCR

ddPCR

RT-qPCR

Data analysis

Scientific communication

Education

Bachelor’s degree in molecular biology

Master’s degree in molecular biology

Tools

ddPCR platform

qPCR instruments

RT-qPCR platforms

Job description

AskBio Inc. in RTP, NC is seeking a Senior Research Associate, Molecular Biodistribution to execute biodistribution and gene expression assays. You will generate high-quality data and interpret results to guide candidate selection, dose strategy, and safety assessment for regulatory submissions.

The role requires hands-on assay development, data analysis, and cross-functional collaboration with Product Development Cores and other teams. Onsite in RTP, NC.