Senior Manager, Clinical Informatics & Data Strategy

Tango Therapeutics; Boston (MA); Hybrid; USD 145,000 - 217,000; Full time

Benefits offered by this job

Hybrid work model

Job summary

Tango Therapeutics is seeking a Senior Manager, Clinical Informatics to design, implement, and continuously improve clinical data flow, integration, analytics, visualization, and reporting across the clinical development portfolio. The role oversees data visualization software, patient randomization and drug supply logistics, and eCOA systems in a validated GxP environment.

You will partner with Clinical Trial Teams and other functions to develop scalable solutions, provide oversight of vendors,

Qualifications

• Extensive experience shaping clinical data flow, reporting, and analytics in regulated settings.
• Experience implementing IRT/eCOA systems and data visualization platforms.
• Proven ability to translate business needs into scalable data solutions.
• Strong knowledge of CDISC standards and CSV/GxP requirements.
• Demonstrated vendor and cross-functional stakeholder management.

Responsibilities

• Define and implement clinical data flow, integration, visualization, and analytics strategies across the portfolio.
• Lead development and maintenance of IRT/eCOA systems and oversee vendor alignment with study objectives.
• Translate requirements into dashboards, reporting, and analytics supporting oversight and decisions.
• Standardize data flows, system integrations, and analytics frameworks for scalability and governance.
• Lead lifecycle management of clinical systems and analytics platforms across studies.
• Oversee vendors and configurations to meet timelines and regulatory expectations.
• Drive adoption of automation, AI, and cloud tech to improve efficiency in a GxP environment.
• Ensure compliance with regulatory validation, data governance, and inspection readiness.

Skills

Clinical data flow

IRT/eCOA systems

Data visualization

Cloud technologies

Data governance

CDISC standards

Vendor management

Stakeholder management

Regulatory compliance

Machine learning

Tools

Spotfire

Elluminate

Power BI

Job description

Tango Therapeutics is seeking a Senior Manager, Clinical Informatics to design, implement, and continuously improve clinical data flow, integration, analytics, visualization, and reporting across the clinical development portfolio. The role oversees data visualization software, patient randomization and drug supply logistics, and eCOA systems in a validated GxP environment.

You will partner with Clinical Trial Teams and other functions to develop scalable solutions, provide oversight of vendors,