Executive Director, Oncology Clinical Development

Tango Therapeutics; Boston (MA); On-site; USD 350,000 - 600,000; Full time

Job summary

Tango Therapeutics is seeking an Executive Director, Clinical Development to lead the clinical development strategy for an early-stage oncology program. Reporting to the President of Research & Development, you will shape study design, governance, and portfolio priorities while representing Tango to the scientific community.

As a senior clinical and scientific leader, you will mentor Medical Directors, drive regulatory strategy, ensure cross-functional execution, and build development

Qualifications

• MD with board certification or eligibility in Medical Oncology or Hematology/Oncology.
• 11+ years of oncology clinical development experience in biotech or pharma.
• Expertise designing and executing oncology clinical trials involving targeted therapies.
• Experience building and leading high-performing clinical development teams.

Responsibilities

• Provide strategic leadership for clinical development, including protocol design, regulatory strategy, and cross-functional execution
• Lead, mentor, and develop physicians, fostering a culture of scientific excellence, integrity and collaboration
• Oversee the preparation of key regulatory documents, including INDs, CTAs, protocols, and briefing packages
• Partner with Project Management and cross-functional leaders to drive governance, operational excellence, and program execution
• Guide clinical trial execution through investigator engagement, patient recruitment strategies, and quality oversight
• Build and maintain strong relationships with key opinion leaders, investigators, and external collaborators
• Represent Tango at scientific meetings, advisory boards, and other external engagements
• Support scientific communications, including publications, abstracts, and presentations

Skills

Strategic leadership

Cross-functional leadership

Regulatory strategy

Communication skills

Mentoring physicians

Education

MD degree

Board-certified in Medical Oncology or Hematology/Oncology

Job description

Tango Therapeutics is seeking an Executive Director, Clinical Development to lead the clinical development strategy for an early-stage oncology program. Reporting to the President of Research & Development, you will shape study design, governance, and portfolio priorities while representing Tango to the scientific community.

As a senior clinical and scientific leader, you will mentor Medical Directors, drive regulatory strategy, ensure cross-functional execution, and build development