Senior IT Director, Genomics & Security (Hybrid)

1000 Pacific Biosciences of California, Inc.; Menlo Park (CA); Hybrid; USD 196,000 - 338,000; Full time

Job summary

1000 Pacific Biosciences of California, Inc. is seeking a Senior Director, IT PacBio to lead a global IT organization spanning enterprise, financial, manufacturing, and R&D systems.

The role partners with executive leadership to enable strategy, operations, and compliant technology solutions in a regulated public-company environment. The successful candidate will manage cybersecurity, audits, and IT governance, while driving modernization, cloud adoption, and cost optimization across on-prem and

Qualifications

• 12+ years of progressive IT experience with leadership at director/senior director level.
• Experience in a public company, preferably life sciences, biotech, or regulated industry.
• Demonstrated experience with SOX compliance, remediation, and audits.
• Hands-on leadership with ISO 27001 security frameworks and certification efforts.
• Strong knowledge of system validation, enterprise architecture, and IT governance.

Responsibilities

• Lead, develop, and scale a high-performing IT organization, including managers and senior technical leaders.
• Define and execute a multi-year IT strategy and technology roadmap aligned with business objectives.
• Own PacBio’s cybersecurity strategy, posture, and operations including prevention, detection, response, and recovery.
• Ensure compliance with ISO 27001, SOX, and other regulatory and audit requirements including SOX audits.
• Oversee enterprise architecture, application portfolio management, and system lifecycle planning.

Skills

IT leadership

SOX compliance

ISO 27001

Executive communication

Risk management

Education

Bachelor’s degree in Information Systems/CS/Engineering

Advanced degree preferred

Tools

Jira Service Desk

SAP

Anaplan

Salesforce

PLM

MES (Siemens Opcenter)

Job description

1000 Pacific Biosciences of California, Inc. is seeking a Senior Director, IT PacBio to lead a global IT organization spanning enterprise, financial, manufacturing, and R&D systems.

The role partners with executive leadership to enable strategy, operations, and compliant technology solutions in a regulated public-company environment. The successful candidate will manage cybersecurity, audits, and IT governance, while driving modernization, cloud adoption, and cost optimization across on-prem and