Global IT Director — Cybersecurity & Compliance Leader

PacBio

Menlo Park (CA)

On-site

USD 196,000 - 338,000

Full time

4 days ago

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Job summary

PacBio in Menlo Park, CA seeks a Senior Director, IT to lead a global IT organization, aligning enterprise systems, manufacturing, R&D, and finance with secure, scalable tech strategies. This role requires deep regulated-industry experience, cybersecurity leadership, risk management, and partnering with executives to drive operational excellence and compliant digital transformation.

Ideal candidate has 12+ years in IT, cloud/on-premise experience, ERP knowledge (SAP), and a track record in

Qualifications

Bachelor’s degree in Information Systems, Computer Science, Engineering, or a related field; advanced degree preferred.
12+ years of progressive IT experience, including significant leadership at the director or senior director level.
Experience in a public company, preferably within life sciences, biotechnology, or a regulated industry.
Demonstrated experience with SOX compliance, remediation, and internal/external audits.
Hands-on leadership experience with ISO 27001 security frameworks and certification efforts.
Strong knowledge of system validation, enterprise architecture, application management, and IT governance.
Proven experience managing hybrid IT environments, including cloud, on-premises infrastructure, HPC, and storage.
Experience with and understanding of Jira Service Desk, SAP, Anaplan, Salesforce, PLM, and MES (Siemens Opcenter).
Provide strategic oversight and guidance for PacBio’s SAP ERP platform, ensuring alignment with business objectives, compliance requirements, and enterprise architecture standards.
Excellent executive communication skills and ability to influence across functions.

Responsibilities

Lead, develop, and scale a high-performing IT organization, including managers and senior technical leaders.
Foster a culture of accountability, service excellence, security awareness, and continuous improvement.
Define and execute a multi-year IT strategy and technology roadmap aligned with PacBio’s business objectives.
Partner with Finance, Manufacturing, R&D, Quality, Legal, and Commercial teams to support business needs.
Own PacBio’s cybersecurity strategy, posture, and operations, including prevention, detection, response, and recovery.
Ensure compliance with ISO 27001, SOX, and other regulatory/audit requirements, including interfacing with SOX auditors.
Lead IT risk management, security governance, incident response planning, and third-party risk management.
Establish and maintain security policies, standards, and controls across infrastructure, applications, and data.
Partner with auditors to support audits and remediation activities.
Ensure IT systems comply with validation and quality requirements (e.g., GxP).
Own IT governance frameworks including enterprise systems development and data governance.
Maintain audit readiness and documentation; oversee enterprise architecture and system lifecycle planning.
Lead hybrid infrastructure operations (on-prem + cloud) and HPC/storage support for R&D workloads.
Drive reliability, scalability, and performance of mission-critical systems.
Lead modernization efforts: cloud adoption, automation, and legacy system rationalization.
Own IT budget, forecasting, and cost optimization; manage strategic vendor relationships.