Global Senior IT Director - Security, Compliance & Strategy

Pacific Biosciences; United States; On-site; USD 180,000 - 240,000; Full time

Job summary

PacBio, NASDAQ: PACB, is seeking a Senior Director, IT to lead the global IT organization supporting enterprise, manufacturing, and R&D information systems. The role partners with executive leadership to enable strategy, operational excellence, and secure, scalable technology solutions.

The ideal candidate has deep experience in regulated environments, ISO 27001 and SOX, and a proven ability to balance strategic vision with operational execution while driving modernization, cloud adoption, and

Qualifications

• Bachelor’s degree in Information Systems, Computer Science, Engineering, or a related field; advanced degree preferred.
• 12+ years IT experience with director or senior director level.
• Experience in a public company, preferably within life sciences or regulated industry.
• SOX compliance experience, remediation, and audits.
• Hands-on leadership with ISO 27001 security frameworks and certification efforts.
• Strong knowledge of enterprise architecture, application management, and IT governance.
• Proven experience managing hybrid IT environments, including cloud, on-premises, HPC, and storage.
• Experience with Jira Service Desk, SAP, Anaplan, Salesforce, PLM, and MES (Siemens Opcenter).
• Strategic oversight for PacBio's SAP ERP platform, aligning with standards and objectives.

Responsibilities

• Lead, develop, and scale a global IT organization with managers and senior leaders.
• Define and execute a multi-year IT strategy and technology roadmap aligned with PacBio’s objectives.
• Partner with Finance, Manufacturing, R&D, Quality, Legal and Commercial teams to support operations.
• Own PacBio’s cybersecurity strategy, posture, and operations, including prevention, detection, response, and recovery.
• Ensure ISO 27001, SOX compliance and coordinate internal and external audits.
• Oversee IT governance, change management, access controls, and data governance.
• Manage IT budget, forecasting, and cost optimization; lead vendor relationships.
• Maintain audit readiness and support audits/remediation activities.

Skills

Leadership

Executive communication

Risk management

IT governance

Education

Bachelor's degree in Information Systems or related field

Advanced degree preferred

Tools

Jira Service Desk

SAP

Anaplan

Salesforce

PLM

MES (Siemens Opcenter)

Job description

PacBio, NASDAQ: PACB, is seeking a Senior Director, IT to lead the global IT organization supporting enterprise, manufacturing, and R&D information systems. The role partners with executive leadership to enable strategy, operational excellence, and secure, scalable technology solutions.

The ideal candidate has deep experience in regulated environments, ISO 27001 and SOX, and a proven ability to balance strategic vision with operational execution while driving modernization, cloud adoption, and