Senior Immunology Scientist for xRNA Biotherapeutics & AOC

U175 (FCRS = US175) Novartis Institutes for BioMedical Research, Inc.; Cambridge (MA); On-site; USD 99,000 - 183,000; Full time

Benefits offered by this job

Health benefits

Life insurance

Disability benefits

401(k) with match

Generous paid time off

Job summary

Novartis Institutes for BioMedical Research, Inc. in Cambridge, MA, is seeking a senior scientist to lead immunology-focused studies and immune profiling for novel biotherapeutics, including AOC/xRNA modalities.

The role involves designing assays with primary cells, coordinating with immunology and translational teams, and communicating results to project teams in a fast-paced Biologics Research Center environment.

Qualifications

• Recent Ph.D. graduate (0-1 year) or MSc in Life Science, preferably immunology or cell biology with 2–5 years of research experience in human immunology or cell biology in industry or academic settings.
• Deep expertise in human immunology and immune assay development, preferably using primary immune cells, multicellular assay systems, tissue-relevant models, or disease-relevant ex vivo platforms.
• Experience assessing immunogenicity, immune activation, cytokine release, anti-drug immune responses, or immune-related liabilities for biologics or emerging therapeutic modalities.
• Demonstrated ability to critically analyze data, learn and combine new techniques quickly, design and prioritize experiments.
• Proficiency with immunological and molecular readouts such as flow cytometry, immunoassays, qPCR, transcriptomics or imaging.
• Scientific curiosity, initiative, commitment, flexibility and good organization and presentation skills.
• Work independently and as a team member with open communication with groups and collaborators.

Responsibilities

• Design, establish, and execute immunology-focused profiling strategies to evaluate immune cell activation, modulation, cytokine release, innate immune sensing, adaptive immune responses, and disease-relevant functional outcomes.
• Collaborate closely with teams in immunology, disease biology, oligonucleotide biology, antibody engineering, bioanalytics, toxicology, and translational medicine to align assay strategy with program needs.
• Regularly communicate and present results, prepare reports, representing the Unit in project teams.

Skills

Immunology

Flow cytometry

Immune profiling

qPCR

Data analysis

Independent work

Team collaboration

Education

Recent PhD or MSc in Life Science

Job description

Novartis Institutes for BioMedical Research, Inc. in Cambridge, MA, is seeking a senior scientist to lead immunology-focused studies and immune profiling for novel biotherapeutics, including AOC/xRNA modalities.

The role involves designing assays with primary cells, coordinating with immunology and translational teams, and communicating results to project teams in a fast-paced Biologics Research Center environment.