Senior Scientist, Immuno-Oncology & Drug Discovery

Novartis AG; Cambridge (MA); On-site; USD 99,000 - 183,000; Full time

Benefits offered by this job

Health benefits

401(k) with company match

Paid time off & holidays

Job summary

Novartis is seeking a Senior Scientist to join the Oncology OIT group in Cambridge, MA. You will perform drug discovery work involving immunology, tumor biology, and cell-based assays to identify and validate novel targets.

The role requires hands-on experience with immune cell assays, molecular biology techniques, and collaboration across a matrixed team. The position offers a competitive salary range and comprehensive US benefits; relocation assistance is available.

Qualifications

• Bachelor's degree in immunology, immuno-oncology, oncology, molecular or cell biology, or a related field is required. A master's degree is preferred.
• 5+ years of relevant laboratory experience in industry
• Knowledge of immunology and expertise in cancer biology and/or immunology are required
• Expertise in tumor immunology, especially T cell mediated anti-tumor activity is highly desired
• Proficiency in cell culture including cell lines and primary cells, and multi-color flow cytometry is required.

Responsibilities

• Support drug screening, target identification and validation using replication-incompetent lentiviruses, mRNA-LNP, cell lines, primary cells, and tissues
• Develop and perform cell-based assays, flow cytometry, and biochemistry-based assays for drug discovery; molecular biology techniques (gel electrophoresis, cloning, qPCR, western blot) when needed
• Conduct biological and pharmacological studies by analyzing preclinical tissue samples from the in vivo team
• Maintain good lab practices, data recording, analysis and documentation
• Collaborate effectively in a matrixed environment and present results in lab/department meetings
• Assist in writing research documents and publications

Skills

Immunology

Cancer biology

Tumor immunology

Cell culture

Flow cytometry

Molecular cloning

qPCR

ELISA

Western blot

Viral production

mRNA-LNP

Gene silencing

Education

Bachelor's degree in immunology, biology or related field

Master's degree preferred

Tools

Flow cytometer

qPCR

ELISA

Western blot

Gel electrophoresis

Molecular cloning

Job description

Novartis is seeking a Senior Scientist to join the Oncology OIT group in Cambridge, MA. You will perform drug discovery work involving immunology, tumor biology, and cell-based assays to identify and validate novel targets.

The role requires hands-on experience with immune cell assays, molecular biology techniques, and collaboration across a matrixed team. The position offers a competitive salary range and comprehensive US benefits; relocation assistance is available.