Senior Gene Therapy Analytical Chemistry Scientist

U014 (FCRS = US014) Novartis Pharmaceuticals Corporation; East Hanover (NJ); On-site; USD 104,000 - 192,000; Full time

Benefits offered by this job

Health benefits

401(k) with company match

Generous time off package

Job summary

Novartis Pharmaceuticals Corporation in East Hanover, NJ, is seeking a Ph.D.-level analytical development scientist to independently design, execute, and interpret complex studies supporting gene therapy product development.

You will develop and transfer analytical methods for product characterization, stability, and process development, using LC, CE, biophysical techniques, and mass spectrometry, while mentoring scientists and ensuring GMP compliance.

Qualifications

• Ph.D. in Chemistry, Biochemistry, Pharmaceutical Sciences, or related discipline with 3+ years of relevant industry experience; OR MS with 4+ years; OR BS with 5+ years.
• Strong foundation in analytical chemistry, protein chemistry, nucleic acid chemistry, or related disciplines.
• Experience with analytical characterization of biologics, viral vectors, or gene therapy products.
• Hands-on experience with one or more analytical platforms such as HPLC/UPLC, CE-SDS, icIEF, SEC-MALS, AUC, mass spectrometry, or particle characterization.
• Demonstrated ability to independently design studies, analyze complex datasets, and solve technical challenges.
• Strong technical writing, communication, and presentation skills.
• Experience with analytical method qualification, transfer, validation, and GMP documentation is preferred.
• Experience supporting AAV and/or lentiviral vector development programs is preferred.

Responsibilities

• Independently design, execute, analyze, and report analytical studies supporting gene therapy development programs.
• Develop, optimize, qualify, and transfer analytical methods for product characterization, process development, and stability assessment.
• Apply scientific expertise to troubleshoot analytical challenges and provide data-driven solutions.
• Perform characterization studies using chromatography(LC), capillary electrophoresis(CE), and biophysical analytical techniques.
• Contribute analytical expertise to cross-functional project teams and effectively communicate scientific findings and recommendations.
• Author and review technical reports, qualification documents, SOPs, and regulatory-supporting documentation.
• Evaluate emerging technologies and contribute to continuous improvement of analytical capabilities.
• Mentor junior scientists and foster a collaborative, innovative, and quality-focused work environment.
• Ensure compliance with GMP, data integrity requirements, and Novartis quality standards.

Skills

Analytical method development

Data analysis

Scientific communication

Education

Ph.D. in Chemistry/Biochemistry/Pharmaceutical Sciences

MS with 4+ years

BS with 5+ years

Tools

HPLC/UPLC

CE-SDS

icIEF

SEC-MALS

Mass spectrometry

Particle characterization

Job description

Novartis Pharmaceuticals Corporation in East Hanover, NJ, is seeking a Ph.D.-level analytical development scientist to independently design, execute, and interpret complex studies supporting gene therapy product development.

You will develop and transfer analytical methods for product characterization, stability, and process development, using LC, CE, biophysical techniques, and mass spectrometry, while mentoring scientists and ensuring GMP compliance.