Senior Gene Therapy Analytical Chemist

Biopharma Careers; East Hanover (NJ); On-site; USD 104,000 - 192,000; Full time

Job summary

Novartis in East Hanover, NJ is seeking a Gene Therapy Analytical Development Chemist who will independently design, execute, and report analytical studies to support gene therapy product development. You will characterize product quality attributes and develop and transfer analytical methods for characterization, process development, and stability assessment.

The role requires solving analytical challenges, mentoring junior scientists, and ensuring GMP and data integrity.

Qualifications

• PhD with 3+ years in industry or MS with 4+ years or BS with 5+ years.
• Strong foundation in analytical chemistry and related disciplines.
• Experience with biologics, viral vectors, or gene therapy analytics.
• Hands-on experience with listed analytical platforms.
• Experience with GMP documentation preferred; experience with AAV/lentiviral vectors preferred.

Responsibilities

• Design, execute, analyze, and report analytical studies for gene therapy programs.
• Develop, qualify, transfer, and optimize analytical methods for characterization and stability.
• Troubleshoot analytical challenges and provide data-driven solutions.
• Perform characterization using chromatography, CE, and biophysical techniques.
• Contribute expertise to cross-functional teams and communicate findings.
• Author and review technical reports, SOPs, and regulatory documents.
• Evaluate emerging technologies and improve analytical capabilities.
• Mentor junior scientists and foster a collaborative environment.
• Ensure GMP compliance and data integrity.

Skills

Analytical chemistry

Protein chemistry

Nucleic acid chemistry

HPLC/UPLC

Mass spectrometry

Education

PhD in Chemistry, Biochemistry, Pharmaceutical Sciences

MS in related field

BS in related field

Tools

HPLC/UPLC

CE-SDS

icIEF

SEC-MALS

Mass spectrometry

Job description

Novartis in East Hanover, NJ is seeking a Gene Therapy Analytical Development Chemist who will independently design, execute, and report analytical studies to support gene therapy product development. You will characterize product quality attributes and develop and transfer analytical methods for characterization, process development, and stability assessment.

The role requires solving analytical challenges, mentoring junior scientists, and ensuring GMP and data integrity.