Expert Science and Technology - Gene Therapy Analytical Development - Chemistry

U014 (FCRS = US014) Novartis Pharmaceuticals Corporation; East Hanover (NJ); On-site; USD 104,000 - 192,000; Full time

Benefits offered by this job

Health benefits

401(k) with company match

Generous time off package

Job summary

Novartis Pharmaceuticals Corporation in East Hanover, NJ, is seeking a Ph.D.-level analytical development scientist to independently design, execute, and interpret complex studies supporting gene therapy product development.

You will develop and transfer analytical methods for product characterization, stability, and process development, using LC, CE, biophysical techniques, and mass spectrometry, while mentoring scientists and ensuring GMP compliance.

Qualifications

• Ph.D. in Chemistry, Biochemistry, Pharmaceutical Sciences, or related discipline with 3+ years of relevant industry experience; OR MS with 4+ years; OR BS with 5+ years.
• Strong foundation in analytical chemistry, protein chemistry, nucleic acid chemistry, or related disciplines.
• Experience with analytical characterization of biologics, viral vectors, or gene therapy products.
• Hands-on experience with one or more analytical platforms such as HPLC/UPLC, CE-SDS, icIEF, SEC-MALS, AUC, mass spectrometry, or particle characterization.
• Demonstrated ability to independently design studies, analyze complex datasets, and solve technical challenges.
• Strong technical writing, communication, and presentation skills.
• Experience with analytical method qualification, transfer, validation, and GMP documentation is preferred.
• Experience supporting AAV and/or lentiviral vector development programs is preferred.

Responsibilities

• Independently design, execute, analyze, and report analytical studies supporting gene therapy development programs.
• Develop, optimize, qualify, and transfer analytical methods for product characterization, process development, and stability assessment.
• Apply scientific expertise to troubleshoot analytical challenges and provide data-driven solutions.
• Perform characterization studies using chromatography(LC), capillary electrophoresis(CE), and biophysical analytical techniques.
• Contribute analytical expertise to cross-functional project teams and effectively communicate scientific findings and recommendations.
• Author and review technical reports, qualification documents, SOPs, and regulatory-supporting documentation.
• Evaluate emerging technologies and contribute to continuous improvement of analytical capabilities.
• Mentor junior scientists and foster a collaborative, innovative, and quality-focused work environment.
• Ensure compliance with GMP, data integrity requirements, and Novartis quality standards.

Skills

Analytical method development

Data analysis

Scientific communication

Education

Ph.D. in Chemistry/Biochemistry/Pharmaceutical Sciences

MS with 4+ years

BS with 5+ years

Tools

HPLC/UPLC

CE-SDS

icIEF

SEC-MALS

Mass spectrometry

Particle characterization

Job description

Job Description Summary

Location: East Hanover, US #onsite Relocation Support: This role is based in East Hanover, NJ, United States. Novartis is unable to offer relocation support: please only apply if accessible. Role Purpose: As a key member of the Gene Therapy Analytical Development Chemistry (AD-Chem) team, the successful candidate will independently design, execute, interpret, and communicate complex analytical studies supporting gene therapy product development. The individual will apply scientific expertise to characterize product quality attributes, develop and optimize analytical methods, solve analytical challenges, and generate data that advances development programs. The role serves as a key technical contributor within multidisciplinary project teams and supports innovation in gene therapy analytics.

What You Will Be Doing

• Independently design, execute, analyze, and report analytical studies supporting gene therapy development programs.
• Develop, optimize, qualify, and transfer analytical methods for product characterization, process development, and stability assessment.
• Apply scientific expertise to troubleshoot analytical challenges and provide data-driven solutions.
• Perform characterization studies using chromatography(LC), capillary electrophoresis(CE), and biophysical analytical techniques.
• Contribute analytical expertise to cross-functional project teams and effectively communicate scientific findings and recommendations.
• Author and review technical reports, qualification documents, SOPs, and regulatory-supporting documentation.
• Evaluate emerging technologies and contribute to continuous improvement of analytical capabilities.
• Mentor junior scientists and foster a collaborative, innovative, and quality-focused work environment.
• Ensure compliance with GMP, data integrity requirements, and Novartis quality standards.

What You Will Bring to the Role

• Ph.D. in Chemistry, Biochemistry, Pharmaceutical Sciences, or related discipline with 3+ years of relevant industry experience; OR MS with 4+ years; OR BS with 5+ years.
• Strong scientific foundation in analytical chemistry, protein chemistry, nucleic acid chemistry, or related disciplines.
• Experience with analytical characterization of biologics, viral vectors, or gene therapy products.
• Hands-on experience with one or more analytical platforms such as HPLC/UPLC, CE-SDS, icIEF, SEC-MALS, AUC, mass spectrometry, or particle characterization techniques.
• Demonstrated ability to independently design studies, analyze complex datasets, and solve technical challenges.
• Strong technical writing, communication, and presentation skills.
• Experience with analytical method qualification, transfer, validation, and GMP documentation is preferred.
• Experience supporting AAV and/or lentiviral vector development programs is preferred.

Salary

The salary for this position is expected to range between $103,600 and $192,400 per year. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Salary Range $103,600.00 - $192,400.00

Benefits

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

• health, life and disability benefits
• 401(k) with company contribution and match
• variety of other benefits
• generous time off package including vacation, personal days, holidays and other leaves

EEO Statement

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.

Accessibility and reasonable accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [e-mail] or call [phone] and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Additional Information

In the context of China Cross-Border Data Transfer (CBDT) policy, if you need to apply for a position in China, please go to the local Recruiting System TaleNov.

Skills Desired

Improving the lives of people living with disease takes more than innovative science. It takes a focus on the needs of people and a community committed to meeting them. It takes a team of people like you. Working together. Learning together. Thriving together. Discover how you can join us in changing people's lives.