Senior Enterprise Architect – AI, Data & Platform Strategy

Vertex Pharmaceuticals Inc (US); Boston (MA); Hybrid; USD 228,000 - 342,000; Full time

Benefits offered by this job

Medical, dental and vision benefits

Paid time off including a week-longamp

Educational assistance and studentloan

Commuting subsidy

Matching charitable donations

401(k) and more

Job summary

Vertex Pharmaceuticals seeks a Senior Enterprise Architect to lead architecture across Commercial and Medical ecosystems, defining reference architectures, patterns, and governance. You will align architecture with enterprise strategies and guide cross-functional teams.

Responsibilities include designing data and integration architectures, ensuring SOX/GxP compliance, and partnering with Product Management, Engineering, and Data teams to deliver scalable, production-ready solutions.

Qualifications

• Deep expertise in enterprise architecture, solution design, and distributed systems.
• Experience with CRM and commercial platforms (Salesforce, Veeva).
• Proven ability to design complex integrations and data architectures at scale.
• Hands-on with cloud and data warehouse platforms (AWS, Azure, Snowflake, Databricks).
• Experience designing AI/ML and LLM-based capabilities; security and compliance knowledge.

Responsibilities

• Define and maintain target-state architecture across Commercial and Medical ecosystems.
• Own integration patterns across Salesforce, Veeva, data platforms, and downstream systems.
• Partner with engineering to define standards across cloud and data platforms; governance.
• Ensure architectures meet SOX, GxP, privacy, and security requirements.
• Translate product requirements into executable architectures and provide guidance.

Skills

Enterprise architecture

CRM experience

Data architecture

Cloud platforms

AI/ML systems

Security/compliance

Engineering guidance

Education

Bachelor's or Master's degree in Computer Science, Engineering, or related field

Job description

Vertex Pharmaceuticals seeks a Senior Enterprise Architect to lead architecture across Commercial and Medical ecosystems, defining reference architectures, patterns, and governance. You will align architecture with enterprise strategies and guide cross-functional teams.

Responsibilities include designing data and integration architectures, ensuring SOX/GxP compliance, and partnering with Product Management, Engineering, and Data teams to deliver scalable, production-ready solutions.