Senior Clinical Operations Lead - Global Trials (Remote)

Travere Therapeutics; Denver (CO); Hybrid; USD 132,000 - 172,000; Full time

Job summary

Travere Therapeutics is seeking a Senior Manager of Clinical Operations to supervise and execute clinical operations for Phase 1–3 trials. You will coordinate daily trial activities, manage CROs, sites, and vendors, and ensure adherence to study plans, SOPs and ICH/GCP.

Responsibilities include budgeting, timelines, SMT leadership, and cross-functional coordination with Biometrics and PV. The role requires global trial experience and up to 20% travel, with onsite work in San Diego and hybrid

Qualifications

• Bachelor's degree or equivalent combination of education and applicable job experience.
• 7+ years of clinical trial experience required with 2+ years managing clinical studies at a sponsor or CRO.
• Experience with global regulatory and compliance requirements (US CFR, EU CTD, ICH E6 R2).
• Phase 1-3 study experience or international studies preferred.

Responsibilities

• Oversee internal study teams, CROs, sites and vendors to ensure trial execution.
• Triage and resolve study issues; escalate as needed.
• Manage study timelines, budgets and SMT for on-time milestones.
• Coordinate cross-functional activities with Biometrics, PV, and other functions.
• Track status, enrollment, regulatory docs and site start-up for trials.
• Develop input into study documents and site-facing materials.
• Monitor CRO budgets and forecast changes with Strategic Procurement.
• Travel 10-20% domestically and internationally.

Skills

Leadership

Communication

Problem-solving

Time management

Cross-functional collaboration

Education

Bachelor's degree or equivalent

7+ years clinical trial experience

2+ years managing studies (sponsor/CRO)

Tools

MS Office

MS Project

Smartsheet

IRT/eTMF systems

Job description

Travere Therapeutics is seeking a Senior Manager of Clinical Operations to supervise and execute clinical operations for Phase 1–3 trials. You will coordinate daily trial activities, manage CROs, sites, and vendors, and ensure adherence to study plans, SOPs and ICH/GCP.

Responsibilities include budgeting, timelines, SMT leadership, and cross-functional coordination with Biometrics and PV. The role requires global trial experience and up to 20% travel, with onsite work in San Diego and hybrid