Senior CFD Scientist, Bioprocess Scale-Up & Transfer

Scorpion Therapeutics; Cambridge (MA); Hybrid; USD 150,000 - 230,000; Full time

Job summary

Scorpion Therapeutics in the United States is seeking a Principal Scientist to lead physics-based engineering simulations within the Digital Insights team, optimizing bioprocess scale-up and technology transfer across biologics, small molecules, and other modalities.

You will conduct CFD and transport phenomena modeling of bioreactor operations, develop scale-down models, and provide technical leadership to drive CMC decisions. Hybrid US-based with ~10% travel.

Qualifications

• PhD or MS in engineering/physics with 6+ years pharma/industrial experience.
• Expertise in CFD and transport phenomena for bioprocess applications.
• Proven ability to validate models with experimental data.
• Strong scripting skills in Python and MATLAB.

Responsibilities

• Conduct CFD and transport phenomena modeling of bioreactor operations.
• Develop and validate scale-down models.
• Provide technical leadership and mentorship.
• Shape modeling standards and roadmaps.
• Support cross-functional teams with simulation insights for CMC decisions.

Skills

CFD tools

Transport phenomena

Bioprocess scale-up

Python

MATLAB

Education

Ph.D. or M.S. in Engineering/Physics

Tools

ANSYS Fluent

COMSOL

OpenFOAM

Job description

Scorpion Therapeutics in the United States is seeking a Principal Scientist to lead physics-based engineering simulations within the Digital Insights team, optimizing bioprocess scale-up and technology transfer across biologics, small molecules, and other modalities.

You will conduct CFD and transport phenomena modeling of bioreactor operations, develop scale-down models, and provide technical leadership to drive CMC decisions. Hybrid US-based with ~10% travel.