Lead CFD Scientist — Bioreactor Scale-Up & Digital Insights

Merck; Boston (MA); Hybrid; USD 173,000 - 273,000; Full time

Benefits offered by this job

Annual bonus

Long-term incentive

Medical, dental, vision

Job summary

Merck is seeking a Principal Scientist to join the Digital Insights team within DSCS Digital Technologies. The role focuses on first-principles CFD and physics-based simulation to drive scale-up decisions for biologics and small-molecule processes.

You will partner with engineers and experimentalists to translate models into actionable CMC strategies. The position emphasizes leadership in modeling, development of scalable workflows, and mentorship of junior scientists within a collaborative,

Qualifications

• PhD/MS/BS with substantial industrial/pharmaceutical experience.
• Experience in transport phenomena, fluid mechanics, and gas–liquid mass transfer.

Responsibilities

• Lead CFD and engineering simulation of bioreactor mixing and gassing.
• Design scale-down models to reproduce manufacturing-scale environments.
• Mentor junior scientists and shape the modeling roadmap.

Skills

CFD

Python

MATLAB

Bioreactors

Transport phenomena

Process Modeling

Education

PhD in Chemical Engineering or closely-related field

MS in Chemical Engineering or closely-related field

BS in Chemical Engineering or closely-related field

Tools

M-Star CFD

ANSYS Fluent

STAR-CCM+

COMSOL

OpenFOAM

Job description

Merck is seeking a Principal Scientist to join the Digital Insights team within DSCS Digital Technologies. The role focuses on first-principles CFD and physics-based simulation to drive scale-up decisions for biologics and small-molecule processes.

You will partner with engineers and experimentalists to translate models into actionable CMC strategies. The position emphasizes leadership in modeling, development of scalable workflows, and mentorship of junior scientists within a collaborative,