Senior Bioprocess Scientist, Purification & CMC Development

AbbVie Inc.; South San Francisco (CA); Sur place; USD 97 000 - 184 000; Plein temps

Résumé du poste

AbbVie Inc. in South San Francisco invites applications for a Senior Scientist I in Bio CMC Purification Process Development.

You will design, optimize, and scale purification steps for monoclonal antibodies and complex biologics within a fast-paced, collaborative lab environment. You will lead technology transfers, define development strategies, and communicate data-driven recommendations to cross-functional teams, ensuring readiness for clinical and regulatory milestones.

Qualifications

• Experience in downstream bioprocess unit operations including affinity, ion-exchange, and hydrophobic-interaction chromatography.
• Proven ability to plan, execute, and prioritize work in a fast-paced, collaborative environment.
• Strong data-analytic skills with ability to interpret complex process data.
• Experience with JMP, Python, or R for data analysis.

Responsabilités

• Develop, optimize, characterize, and scale up purification processes for monoclonal antibodies and complex biologics.
• Lead technology transfer to GMP sites; author transfer packages and support facility readiness.
• Develop viral clearance strategy and oversee studies with contract laboratories.
• Make data-driven recommendations and communicate risks to stakeholders.
• Mentor and train junior scientists.
• Stay current with literature, regulatory guidance, and industry trends.

Connaissances

Downstream bioprocess operations

Process development leadership

Biopharmaceutical purification

Data analysis

Formation

Bachelor’s Degree or equivalent education

Master’s Degree or equivalent education

PhD in a related field

Outils

JMP

Python

R

AKTA chromatography

GoSilico

CADET

gPROMS

Tecan or Hamilton automation

Description du poste

AbbVie Inc. in South San Francisco invites applications for a Senior Scientist I in Bio CMC Purification Process Development.

You will design, optimize, and scale purification steps for monoclonal antibodies and complex biologics within a fast-paced, collaborative lab environment. You will lead technology transfers, define development strategies, and communicate data-driven recommendations to cross-functional teams, ensuring readiness for clinical and regulatory milestones.